Evidence map›Paper›PMID 30409992›Full record

ArticleScientific reports2018

Altered Placental Chorionic Arterial Biomechanical Properties During Intrauterine Growth Restriction.

Shier Nee Saw, Jess Jia Hwee Tay, Yu Wei Poh, Liying Yang, Wei Ching Tan, Lay Kok Tan, Alys Clark, Arijit Biswas, Citra Nurfarah Zaini Mattar, Choon Hwai Yap

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Feto-placental blood vessel development.Development (Cambridge, England) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Shier Nee SawDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
Jess Jia Hwee TayDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
Yu Wei PohDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
Liying YangDepartment of Obstetrics & Gynecology, Singapore General Hospital, Singapore, Singapore.
Wei Ching TanDepartment of Obstetrics & Gynecology, Singapore General Hospital, Singapore, Singapore.
Lay Kok TanDepartment of Obstetrics & Gynecology, Singapore General Hospital, Singapore, Singapore.
Alys ClarkAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Arijit BiswasDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health Systems, Singapore, Singapore.
Citra Nurfarah Zaini MattarDepartment of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health Systems, Singapore, Singapore.
Choon Hwai YapDepartment of Biomedical Engineering, National University of Singapore, Singapore, Singapore. bieyapc@nus.edu.sg.ORCID http://orcid.org/0000-0003-2918-3077
National University of Singapore · SGSingapore General Hospital · SGUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine growth restriction (IUGR) is a pregnancy complication due to placental dysfunction that prevents the fetus from obtaining enough oxygen and nutrients, leading to serious mortality and morbidity risks. There is no treatment for IUGR despite having a prevalence of 3% in developed countries, giving rise to an urgency to improve our understanding of the disease. Applying biomechanics investigation on IUGR placental tissues can give important new insights. We performed pressure-diameter mechanical testing of placental chorionic arteries and found that in severe IUGR cases (RI > 90

Indexed as

ArteriesBiomechanical PhenomenaChorionic VilliFemaleFetal Growth RetardationHemodynamicsHumansModels, BiologicalPlacental CirculationPregnancyPrevalencePulse Wave Analysis

Identifiers

PMID30409992
PMCPMC6224524
OpenAlexW2898928934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.