ArticleNature communications2018
Overexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
120 citing papers in PubMed.
- Exogenous 24-Epibrassinolide Alleviates Postharvest Chilling Injury in Green Pepper Fruit Associated with Enhanced Antioxidant Defense and Reduced Membrane Damage.Plants (Basel, Switzerland) · 2026Article
- Conserved leaf-root metabolomic network asymmetry underpins divergent drought strategies.The Plant cell · 2026Article
- Evolutionary shifts in plant adaptation mediated by phytohormones.Plant communications · 2026Review
- Phytohormone-Mediated Regulation of Plant Cold Stress Tolerance: Signaling, Hormonal Crosstalk, and Translational Perspectives.International journal of molecular sciences · 2026Review
- Genome-wide identification and expression analysis of salt-responsive bHLH transcription factors in the wheat (Frontiers in plant science · 2026Article
- Synthesis and biological evaluation of new brassinosteroid analogs with C-22 benzoate function.Beilstein journal of organic chemistry · 2026Article
- Genomic and Transcriptomic Insights into Stage-Specific Drought Resilience in Diverse Myanmar Rice Germplasm.Rice (New York, N.Y.) · 2025Article
- Epibrassinolide seed priming alleviates alkaline stress by enhancing antioxidant defense in dragonhead plants.Scientific reports · 2025Article
- Emerging Mechanisms of Plant Responses to Abiotic Stress.Plants (Basel, Switzerland) · 2025Review
- Specificity of brassinosteroid perception and its integration at signaling crossroads in vascular development.The Plant journal : for cell and molecular biology · 2025Review
- Keeping cool: A brassinosteroid receptor BRL3 helps Arabidopsis cope with heat stress.Plant physiology · 2025Article
- Unearthing the hidden organ: vital role of the root in drought tolerance of plants.Plant molecular biology · 2025Review
- Scaffold protein RhCASPL1D1 stabilizes RhPIP2 aquaporins and promotes flower recovery after dehydration in rose (Horticulture research · 2025Article
- Growth Cost and Transport Efficiency Tradeoffs Define Root System Optimization Across Varying Developmental Stages and Environments in Arabidopsis.bioRxiv : the preprint server for biology · 2025Article
- Research on the Hormonomics of ThreeAntioxidants (Basel, Switzerland) · 2025Article
- On Selecting Robust Approaches for Learning Predictive Biomarkers in Metabolomics Data Sets.Analytical chemistry · 2025Article
- Comparative RNA sequencing-based transcriptome profiling of Quercur robur: specific sets of genes involved in taproot and lateral roots emergence.Tree physiology · 2025Article
- NAC transcription factors are key regulators of Brassinolide-Enhanced drought tolerance in Camellia oil tree.BMC plant biology · 2025Article
- Roles of hormones in regulating root growth-water interactions.Journal of experimental botany · 2025Review
- Increased chloroplast area in the rice bundle sheath through cell-specific perturbation of brassinosteroid signaling.Plant physiology · 2025Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. However, plants with enhanced drought resistance usually display lower growth, highlighting the need for strategies to uncouple drought resistance from growth. Here, we show that overexpression of BRL3, a vascular-enriched member of the brassinosteroid receptor family, can confer drought stress tolerance in Arabidopsis. Whereas loss-of-function mutations in the ubiquitously expressed BRI1 receptor leads to drought resistance at the expense of growth, overexpression of BRL3 receptor confers drought tolerance without penalizing overall growth. Systematic analyses reveal that upon drought stress, increased BRL3 triggers the accumulation of osmoprotectant metabolites including proline and sugars. Transcriptomic analysis suggests that this results from differential expression of genes in the vascular tissues. Altogether, this data suggests that manipulating BRL3 expression could be used to engineer drought tolerant crops.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.