Evidence map›Paper›PMID 30409850›Full record

ArticleAJNR. American journal of neuroradiology2018

Differentiation of Hemorrhage from Iodine Using Spectral Detector CT: A Phantom Study.

S Van Hedent, N Große Hokamp, K R Laukamp, N Buls, R Kessner, B Rose, P Ros, D Jordan

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S Van HedentFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.) steven.vanhedent@case.edu.ORCID 0000-0002-5994-9507
N Große HokampFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.).ORCID 0000-0001-7928-0487
K R LaukampFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.).ORCID 0000-0002-5600-5914
N BulsVrije Universiteit Brussel (S.V.H., N.B.), Brussels, Belgium.ORCID 0000-0003-2830-6899
R KessnerFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.).ORCID 0000-0002-4293-3226
B RosePathology (B.R.), University Hospitals Cleveland Medical Center, Cleveland, Ohio.ORCID 0000-0001-5581-8561
P RosFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.).ORCID 0000-0003-3974-0797
D JordanFrom the Departments of Radiology (S.V.H., N.G.H., K.R.L., R.K., P.R., D.J.).ORCID 0000-0002-4738-9696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeConventional CT often cannot distinguish hemorrhage from iodine extravasation following reperfusion therapy for acute ischemic stroke. We investigated the potential of spectral detector CT in differentiating these lesions. MATERIALS AND

methodsCentrifuged blood with increasing hematocrit (5%-85%) was used to model hemorrhage. Pure blood, blood-iodine mixtures (75/25, 50/50, and 25/75 ratios), and iodine solutions (0-14 mg I/mL) were scanned in a phantom with attenuation ranging from 12 to 75 HU on conventional imaging. Conventional and virtual noncontrast attenuation was compared and investigated for correlation with calculation of relative virtual noncontrast attenuation. Values for all investigated categories were compared using the Mann-Whitney

resultsConventional image attenuation was not significantly different among all samples containing blood (

conclusionsSpectral detector CT can accurately differentiate blood from iodinated contrast in a phantom setting.

Indexed as

Cerebral HemorrhageContrast MediaExtravasation of Diagnostic and Therapeutic MaterialsHumansIodinePhantoms, ImagingSensitivity and SpecificityStrokeTomography, X-Ray ComputedContrast MediaIodine

Identifiers

PMID30409850
PMCPMC7655395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.