Evidence map›Paper›PMID 30409797›Full record

ArticleHaematologica2019

A new BCR-ABL1

Roberto Bernardoni, Giorgia Giordani, Elisabetta Signorino, Sara Monticelli, Francesca Messa, Monica Pradotto, Valentina Rosso, Enrico Bracco, Angela Giangrande, Giovanni Perini and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Validation of aHaematologica · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Roberto BernardoniDepartment of Pharmacy and Biotechnology (FABIT), University of Bologna, Italy roberto.bernardoni@unibo.it.
Giorgia GiordaniDepartment of Pharmacy and Biotechnology (FABIT), University of Bologna, Italy.
Elisabetta SignorinoDepartment of Clinical and Biological Sciences, University of Turin, Italy.
Sara MonticelliDepartment of Pharmacy and Biotechnology (FABIT), University of Bologna, Italy.
Francesca MessaDepartment of Pharmacy and Biotechnology (FABIT), University of Bologna, Italy.
Monica PradottoDepartment of Clinical and Biological Sciences, University of Turin, Italy.
Valentina RossoDepartment of Clinical and Biological Sciences, University of Turin, Italy.
Enrico BraccoDepartment of Oncology, University of Turin, Italy.
Angela GiangrandeInstitut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP 67404 Illkirch, France.
Giovanni PeriniDepartment of Pharmacy and Biotechnology (FABIT), University of Bologna, Italy.
Giuseppe SaglioDepartment of Clinical and Biological Sciences, University of Turin, Italy.
Daniela CilloniDepartment of Clinical and Biological Sciences, University of Turin, Italy daniela.cilloni@unito.it.
University of Turin · ITUniversity of Bologna · ITCentre National de la Recherche Scientifique · FR

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NIH HHS P40 OD018537
6 · The paper itself

Abstract

The oncoprotein BCR-ABL1 triggers chronic myeloid leukemia. It is clear that the disease relies on constitutive BCR-ABL1 kinase activity, but not all the interactors and regulators of the oncoprotein are known. We describe and validate a

Indexed as

Animals, Genetically ModifiedFusion Proteins, bcr-ablGene Expression Regulation, LeukemicLeukemia, Myelogenous, Chronic, BCR-ABL PositiveAnimalsDisease Models, AnimalDrosophila melanogasterHumansBCR-ABL1 fusion protein, humanFusion Proteins, bcr-abl

Identifiers

PMID30409797
PMCPMC6442973
OpenAlexW2899993940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.