Evidence map›Paper›PMID 30409515›Full record

ArticleBiochimica et biophysica acta. Biomembranes2018

Effect of late endosomal DOBMP lipid and traditional model lipids of electrophysiology on the anthrax toxin channel activity.

Nnanya Kalu, Yoav Atsmon-Raz, Sanaz Momben Abolfath, Laura Lucas, Clare Kenney, Stephen H Leppla, D Peter Tieleman, Ekaterina M Nestorovich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nnanya KaluDepartment of Biology, The Catholic University of America, 620 Michigan Ave NE, Washington 20064, DC, USA.
Yoav Atsmon-RazDepartment of Biological Sciences, Centre for Molecular Simulation, University of Calgary, 2500 University Drive NW, Calgary T2N 1N4, Alberta, Canada. Electronic address: Yoav.atsmonraz@ucalgary.ca.
Sanaz Momben AbolfathDepartment of Biology, The Catholic University of America, 620 Michigan Ave NE, Washington 20064, DC, USA.
Laura LucasDepartment of Biology, The Catholic University of America, 620 Michigan Ave NE, Washington 20064, DC, USA.
Clare KenneyDepartment of Biology, The Catholic University of America, 620 Michigan Ave NE, Washington 20064, DC, USA.
Stephen H LepplaMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda 20892, MD, USA.
D Peter TielemanDepartment of Biological Sciences, Centre for Molecular Simulation, University of Calgary, 2500 University Drive NW, Calgary T2N 1N4, Alberta, Canada.
Ekaterina M NestorovichDepartment of Biology, The Catholic University of America, 620 Michigan Ave NE, Washington 20064, DC, USA. Electronic address: Nestorovich@cua.edu.
University of America · USUniversity of Calgary · CANational Institute of Allergy and Infectious Diseases · US

Funding

Vaccines and Therapeutics for AnthraxZIAAI000929 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LEPPLA, STEPHEN · 2009 to 2025
$15.9M
OBSTRUCTING TOXIN'S PATHWAYS: UNIVERSAL INHIBITORS OF BINARY BACTERIAL TOXINSR15AI099897 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI NESTOROVICH, EKATERINA · 2014 to 2014
$423k
NIAID NIH HHS R15 AI099897
6 · The paper itself

Abstract

Anthrax toxin action requires triggering of natural endocytic transport mechanisms whereby the binding component of the toxin forms channels (PA

Indexed as

Antigens, BacterialBacterial ToxinsBiochemical PhenomenaBiological TransportElectrophysiological PhenomenaEndosomesLipid BilayersMolecular Dynamics SimulationProtein Bindinganthrax toxinAntigens, BacterialBacterial ToxinsLipid BilayersBacillus anthracisBinary anthrax toxinEndosomal intraluminal vesiclesMembrane lipid dynamicsModel lipid bilayersMolecular dynamics simulations

Identifiers

PMID30409515
PMCPMC6814629
OpenAlexW2888273939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.