ReviewJournal of developmental origins of health and disease2019
Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review.
Review in Journal of developmental origins of health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Effectiveness of Digital Tools on Lifestyle & Health-Related Outcomes Across the Full Continuum of the Maternal Journey: A Systematic Review.Current obesity reports · 2026Pooled it
- Nutrition interventions in the first 1000 days and long-term health outcomes: a systematic review.Pediatric research · 2025Pooled it
- The effectiveness of interventions during the first 1,000 days to improve energy balance-related behaviors or prevent overweight/obesity in children from socio-economically disadvantaged families of high-income countries: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- First 1000 Days Strategies to Prevent Childhood Obesity: A Narrative Review and Recommendations From the EndObesity Consortium.Pediatric obesity · 2026Review
- Article
- Article
- A scoping review of costing methodologies used to assess interventions for underserved pregnant people and new parents.International journal for equity in health · 2024Article
- Association of perinatal characteristics with biomarkers of stress and inflammation in young adults: An exploratory study.Comprehensive psychoneuroendocrinology · 2024Article
- Observational
- Predicting and comparing the long-term impact of lifestyle interventions on individuals with eating disorders in active population: a machine learning evaluation.Frontiers in nutrition · 2024Article
- Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course.Nature reviews. Cardiology · 2023Review
- Fetal Growth Trajectories and Measures of Insulin Resistance in Young Adults.The Journal of clinical endocrinology and metabolism · 2023Article
- Prevention of alcohol related harm though preconception care: A scoping review of barriers and enablers.Dialogues in health · 2022Article
- Eating for 2: A Systematic Review of Dutch App Stores for Apps Promoting a Healthy Diet during Pregnancy.Current developments in nutrition · 2022Article
- Preconception and early-pregnancy risk prediction for birth complications: development of prediction models within a population-based prospective cohort.BMC pregnancy and childbirth · 2022Article
- A meta-review of systematic reviews of lifestyle interventions for reducing gestational weight gain in women with overweight or obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Review
- Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts.International journal of obesity (2005) · 2021Article
- Gestational sleep deprivation is associated with higher offspring body mass index and blood pressure.Sleep · 2020Article
- Psychosocial Stress, Sedentary Behavior, and Physical Activity during Pregnancy among Canadian Women: Relationships in a Diverse Cohort and a Nationwide Sample.International journal of environmental research and public health · 2019Article
- Impacts of a perinatal exposure to manganese coupled with maternal stress in rats: Learning, memory and attentional function in exposed offspring.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Adverse exposures during fetal life and the postnatal period influence physical, cognitive and emotional development, and predispose to an increased risk of various chronic diseases throughout the life course. Findings from large observational studies in various populations and experimental animal studies have identified different modifiable risk factors in early life. Adverse maternal lifestyle factors, including overweight, unhealthy diet, sedentary behavior, smoking, alcohol consumption and stress in the preconception period and during pregnancy, are the most common modifiable risk factors leading to a suboptimal in-utero environment for fetal development. In the postnatal period, breastfeeding, infant growth and infant dietary intake are important modifiable factors influencing long-term offspring health outcomes. Despite the large amount of findings from observational studies, translation to lifestyle interventions seems to be challenging. Currently, randomized controlled trials focused on the influence of lifestyle interventions in these critical periods on short-term and long-term maternal and offspring health outcomes are scarce, have major limitations and do not show strong effects on maternal and offspring outcomes. New and innovative approaches are needed to move from describing these causes of ill-health to start tackling them using intervention approaches. Future randomized controlled lifestyle intervention studies and innovative observational studies, using quasi-experimental designs, are needed focused on the effects of an integrated lifestyle advice from preconception onwards on pregnancy outcomes and long-term health outcomes in offspring on a population level.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.