Trial reportJournal of neuroengineering and rehabilitation2018
Time course of changes in motor-cognitive exergame performances during task-specific training in patients with dementia: identification and predictors of early training response.
Trial report in Journal of neuroengineering and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Technology-Assisted Cognitive Motor Dual-Task Rehabilitation in Chronic Age-Related Conditions: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Effect of virtual reality exercise on interventions for patients with Alzheimer's disease: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Virtual reality-based training may improve visual memory and some aspects of sustained attention among healthy older adults - preliminary results of a randomized controlled study.BMC psychiatry · 2024Trial
- Effect of exergaming on wellbeing of residents in a nursing home: a single blinded intervention study.Aging clinical and experimental research · 2022Trial
- A facility-based "brain gym": feasibility and preliminary effectiveness of a long-duration, low-frequency dual-task and exergaming intervention in older adults.Frontiers in psychology · 2026Article
- Are gamifying exergames the future of intervention for people with dementia? Systematic review and meta-analysis.Frontiers in human neuroscience · 2026Review
- Gender- and domain-specific effects of a 6-month multidimensional exercise program on attention and verbal fluency in physically inactive older adults.Frontiers in aging · 2026Article
- Article
- The overlooked role of exergames in cognitive-motor neurorehabilitation: a systematic review.NPJ digital medicine · 2025Article
- Dementia and Video Games: Systematic and Bibliographic Review.Healthcare (Basel, Switzerland) · 2024Review
- Neurorehabilitation including Virtual-Reality-Based Balance Therapy: Factors Associated with Training Response.Brain sciences · 2024Article
- The "FitBrain" program: implementing exergaming & dual-task exercise programs in outpatient clinical settings.Frontiers in sports and active living · 2024Article
- The impact of a coronavirus disease 2019 pandemic-related interruption of regular physical rehabilitation on functional abilities in a patient with two chronic neurological diseases: a case report.Journal of medical case reports · 2021Article
- Psychometric Properties of the Proxy-Reported Life-Space Assessment in Institutionalized Settings (LSA-IS-Proxy) for Older Persons with and without Cognitive Impairment.International journal of environmental research and public health · 2021Article
- Effectiveness and sustainability of a motor-cognitive stepping exergame training on stepping performance in older adults: a randomized controlled trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2020Article
- Combining Stochastic Resonance Vibration With Exergaming for Motor-Cognitive Training in Long-Term Care; A Sham-Control Randomized Controlled Pilot Trial.Frontiers in medicine · 2020Article
- Bridging game metrics and user perception in remote virtual reality exergames: Lessons from a COVID-19 home-based study.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome studies have already suggested that exergame interventions can be effective to improve physical, cognitive, motor-cognitive, and psychological outcomes in patients with dementia (PwD). However, little is known about the training volume required to induce such positive effects and the inter-individual differences in training response among PwD. The aim of the study was to analyze the time course of changes in motor-cognitive exergame performances during a task-specific training program and to identify predictors of early training response in PwD.
methodsSecondary analyses of data from the intervention group (IG) of a randomized, placebo-controlled trial to improve motor-cognitive performances in PwD. Fifty-six geriatric patients with mild-to-moderate dementia randomized to the IG underwent a 10-week, task-specific training program (2×/week) on an exergame-based balance training system (Physiomat®), combining postural control tasks with cognitive tasks of an established neuropsychological test (Trail Making Test). Main outcome was the time required to complete different Physiomat®-Tasks (PTs) assessed at baseline (T1), training session 7 (TS7) and 14 (TS14), and post-intervention after 20 training sessions (T2). Reliable change indices were used to identify early responders from T1 to TS7. A multivariate logistic regression analysis was performed to determine independent predictors of early training response.
resultsCompletion time significantly improved already from T1 to TS7 in all PTs (p ≤ .001-.006), with moderate to very large effect sizes (r = .38-.52; Cohen's d = .85-1.45). For most PTs, significant progressive improvements from TS7 to TS14 and TS14 to T2 were not observed. Thirty-one (59.6%) participants were classified as early responders and 21 (40.4%) as non-early responders. Lower baseline exergame performance and lower visuospatial and divided attention abilities were independently associated with early training response.
conclusionsSubstantial task-specific improvements in complex motor-cognitive exergame performances can be obtained within a surprisingly short intervention period in PwD. Our results confirm that not only an excellent training response can be achieved in this patient population, but also that more vulnerable patients with greater deficits in domain-specific cognitive functions associated with fall risk may even reap the most and fastest benefit from motor-cognitive exergame interventions.
trial registrationISRCTN registry, ISRCTN37232817 (retrospectively registered on 04/02/2012).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.