Evidence map›Paper›PMID 30409076›Full record

ArticleTissue barriers2018

Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs.

Honglei Chen, Rong Lu, Yong-Guo Zhang, Jun Sun

Open access · bronzeAbstract read
In one paragraph

Article in Tissue barriers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 91 citations in OpenAlex.

  1. Review
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  12. Emerging role of vitamin DAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  13. Vitamin DEuropean journal of nutrition · 2024
    Article
  14. Article
  15. Vitamin DEuropean journal of cell biology · 2023
    Article
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  18. Vitamin D Promotes Mucosal Barrier System of Fish Skin Infected withInternational journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Honglei Chena Department of Biochemistry , Rush University , Chicago , IL , USA.ORCID 0000-0001-9832-1336
Rong Lub Division of Gastroenterology and Hepatology, Department of Medicine , University of Illinois at Chicago , Chicago , IL , USA.
Yong-Guo Zhangb Division of Gastroenterology and Hepatology, Department of Medicine , University of Illinois at Chicago , Chicago , IL , USA.
Jun Sunb Division of Gastroenterology and Hepatology, Department of Medicine , University of Illinois at Chicago , Chicago , IL , USA.ORCID 0000-0001-7465-3133
University of Illinois Chicago · USRush University · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK114126
6 · The paper itself

Abstract

Vitamin D deficiency has been linked to various inflammatory diseases in lungs, including pneumonia, asthma and chronic obstructive pulmonary disease. However, the mechanisms by which vitamin D and vitamin D receptor reduce inflammation in lung diseases remain poorly understood. In this study, we investigated the expression and cell-specific distribution of tight and adherens junctions in the lungs of vitamin D receptor-deficient (VDR

Indexed as

Adherens JunctionsAnimalsCapillary PermeabilityFemaleLungMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, CalcitriolTight JunctionsVitamin D DeficiencyReceptors, Calcitrioladherens junctionschronic pneumoniaClaudinCOPDepithelial cellslung permeabilitytight junctionsVitamin Dvitamin D receptor

Identifiers

PMID30409076
PMCPMC6389123
OpenAlexW2900218132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.