ArticlePloS one2018
Cost-effectiveness of screening for chronic hepatitis B and C among migrant populations in a low endemic country.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- A systematic review of barriers and facilitators for hepatitis B and C screening among migrants in the EU/EEA region.Frontiers in public health · 2023Pooled it
- Cost-effectiveness of community interventions to promote awareness, testing and treatment of hepatitis B and C in migrant populations in Catalonia.Scientific reports · 2026Article
- Article
- Estimating the impact of displacement from Ukraine on HBV and HCV prevalence among migrants in the European Union, 2024: a modeling study.The Lancet regional health. Europe · 2025Article
- Hepatitis B susceptibility and subsequent vaccination in priority populations across an Australian sentinel surveillance network, 2017Epidemiology and infection · 2025Article
- Integrating hepatitis B virus, hepatitis C virus and human immunodeficiency virus screening for migrants from endemic countries into travel-related and sexual health care in Amsterdam, the Netherlands.Frontiers in public health · 2025Article
- Reaching Syrian migrants through Dutch municipal registries for hepatitis B and C point-of-care testing.PloS one · 2025Article
- Implementation of the HepCBMJ open · 2023Article
- An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example.Medical decision making : an international journal of the Society for Medical Decision Making · 2023Article
- Routine screening of emergency admissions at risk of chronic hepatitis (SEARCH) identifies and links hepatitis B cases to care.Liver international : official journal of the International Association for the Study of the Liver · 2023Article
- A Tutorial on Time-Dependent Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example.Medical decision making : an international journal of the Society for Medical Decision Making · 2023Article
- Cascade of care among hepatitis B patients in Maastricht, the Netherlands, 1996 to 2018.Journal of virus eradication · 2022Article
- Monitoring progress towards elimination of hepatitis B and C in the EU/EEA.PLOS global public health · 2022Article
- Hepatitis B screening among immigrants: How to successfully reach the Moroccan community.Journal of viral hepatitis · 2021Article
- Time for universal hepatitis B screening for Australian adults.The Medical journal of Australia · 2021Article
- A global investment framework for the elimination of hepatitis B.Journal of hepatology · 2021Article
- Article
- Screening approach among newly arrived asylum seekers: experience in a primary health care setting in Piacenza, Emilia Romagna, Northern Italy.Journal of preventive medicine and hygiene · 2020Article
- The Cost-Effectiveness of Hepatitis C Virus Screening Strategies among Recently Arrived Migrants in the Netherlands.International journal of environmental research and public health · 2020Article
- Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands.BMC public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic infection with hepatitis B or C virus (HBV/HCV) can progress to cirrhosis, liver cancer, and even death. In a low endemic country as the Netherlands, migrants are a key risk group and could benefit from early diagnosis and antiviral treatment. We assessed the cost-effectiveness of screening foreign-born migrants for chronic HBV and/or HCV using a societal perspective.
methodsThe cost-effectiveness was evaluated using a Markov model. Estimates on prevalence, screening programme costs, participation and treatment uptake, transition probabilities, healthcare costs, productivity losses and utilities were derived from the literature. The cost per Quality Adjusted Life Year (QALY) gained was estimated and sensitivity analyses were performed.
resultsFor most migrant groups with an expected high number of chronically infected cases in the Netherlands combined screening is cost-effective, with incremental cost-effectiveness ratios (ICERs) ranging from €4,962/QALY gained for migrants originating from the Former Soviet Union and Vietnam to €9,375/QALY gained for Polish migrants. HBV and HCV screening proved to be cost-effective for migrants from countries with chronic HBV or HCV prevalence of ≥0.41% and ≥0.22%, with ICERs below the Dutch cost-effectiveness reference value of €20,000/QALY gained. Sensitivity analysis showed that treatment costs influenced the ICER for both infections.
conclusionsFor most migrant populations in a low-endemic country offering combined HBV and HCV screening is cost-effective. Implementation of targeted HBV and HCV screening programmes to increase early diagnosis and treatment is important to reduce the burden of chronic hepatitis B and C among migrants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.