Evidence map›Paper›PMID 30407600›Full record

ArticleSleep2019

Insomnia and suicidal ideation in nonaffective psychosis.

Brian J Miller, Carmen B Parker, Mark H Rapaport, Peter F Buckley, William V McCall

Open access · bronzeAbstract read
In one paragraph

Article in Sleep, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Results of a pilot randomized controlled trial of CBT-I for veterans with serious mental illness and insomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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  15. Genetic evidence for a potential causal relationship between insomnia symptoms and suicidal behavior: a Mendelian randomization study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
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  16. Review
  17. Insomnia and suicide as reported adverse effects of second-generation antipsychotics and mood stabilizers.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Brian J MillerDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, GA.
Carmen B ParkerDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Mark H RapaportDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA.
Peter F BuckleySchool of Medicine, Virginia Commonwealth University, Richmond, VA.
William V McCallDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, GA.
Augusta University · USEmory University · USUniversity of Pennsylvania · USVirginia Commonwealth University · US

Funding

A Potential State and Relapse Predictive Marker in SchizophreniaK23MH098014 · NIMH · AUGUSTA UNIVERSITY · PI MILLER, BRIAN JAMES · 2012 to 2016
$921k
NIMH NIH HHS K23 MH098014
6 · The paper itself

Abstract

Study Objectives: Insomnia is a common symptom in the clinical course of schizophrenia. There is a robust association between insomnia and suicidality in other psychiatric disorders. Two previous studies found associations between insomnia and suicide attempt or completed suicide in patients with schizophrenia. We hypothesized that greater insomnia would be associated with greater levels of suicidal ideation in patients with schizophrenia and other nonaffective psychoses. Methods: We recruited 108 inpatients and outpatients age 18-65 between July 2010 and July 2016 with DSM-IV nonaffective psychosis (schizophrenia, schizoaffective disorder, or schizophreniform disorder). We investigated relationships between current insomnia (Insomnia Severity Index [ISI]), suicidal ideation over the past week, and lifetime history of suicide attempt (Beck Scale for Suicide Ideation [BSS]) in regression analyses. Results: After controlling for potential confounders, insomnia was a significant indicator of suicidal ideation (β = 0.27, p = 0.032). Insomnia was also a significant indicator of a high BSS score (≥16; OR = 1.14, 95% CI: 1.01-1.28, p = 0.029). Furthermore, participants with severe insomnia were almost 15 times more likely to have a lifetime history suicide attempt than participants without current insomnia (OR = 14.8, 95% CI: 1.4-157, p = 0.025). Insomnia was also an indicator of greater PANSS total (β = 0.33, p = 0.001), positive subscale (β = 0.32, p = 0.002), and general subscale (β = 0.40, p < 0.001) scores. Conclusions: Insomnia is associated with suicidal ideation, lifetime suicide attempt, and greater psychopathology in patients with schizophrenia. Our findings suggest that formal assessment of insomnia may be germane to the clinical care of patients with schizophrenia as a marker of suicide risk and symptom severity.

Indexed as

Suicidal IdeationAdolescentAdultAgedFemaleHumansMaleMiddle AgedOutpatientsPsychotic DisordersRisk FactorsSchizophreniaSleep Initiation and Maintenance DisordersSuicide, AttemptedYoung Adult

Identifiers

PMID30407600
PMCPMC6369728
OpenAlexW2899941808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.