Evidence map›Paper›PMID 30407441›Full record

ReviewMicromachines2016

Optofluidic Device Based Microflow Cytometers for Particle/Cell Detection: A Review.

Yushan Zhang, Benjamin R Watts, Tianyi Guo, Zhiyi Zhang, Changqing Xu, Qiyin Fang

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yushan ZhangSchool of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. zhang749@mcmaster.ca.
Benjamin R WattsArtIC Photonics, 260 Terence Matthews Cres, Ottawa, ON K2M 2C7, Canada. benjamin.r.watts@gmail.com.
Tianyi GuoSchool of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. guot2@mcmaster.ca.
Zhiyi ZhangInformation and Communication Technologies, National Research Council of Canada, 1200 Montreal Road, Ottawa, ON K1A 0R6, Canada. zhiyi.zhang@nrc-cnrc.gc.ca.
Changqing XuDepartment of Engineering Physics, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. cqxu@mcmaster.ca.
Qiyin FangDepartment of Engineering Physics, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. qiyin.fang@mcmaster.ca.ORCID 0000-0003-2786-9884
McMaster University · CANational Research Council Canada · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN/262023-2013Ontario Research Fund RE-WR-10
6 · The paper itself

Abstract

Optofluidic devices combining micro-optical and microfluidic components bring a host of new advantages to conventional microfluidic devices. Aspects, such as optical beam shaping, can be integrated on-chip and provide high-sensitivity and built-in optical alignment. Optofluidic microflow cytometers have been demonstrated in applications, such as point-of-care diagnostics, cellular immunophenotyping, rare cell analysis, genomics and analytical chemistry. Flow control, light guiding and collecting, data collection and data analysis are the four main techniques attributed to the performance of the optofluidic microflow cytometer. Each of the four areas is discussed in detail to show the basic principles and recent developments. 3D microfabrication techniques are discussed in their use to make these novel microfluidic devices, and the integration of the whole system takes advantage of the miniaturization of each sub-system. The combination of these different techniques is a spur to the development of microflow cytometers, and results show the performance of many types of microflow cytometers developed recently.

Indexed as

microfabricationmicroflow cytometermicrofluidicsoptofluidic device

Identifiers

PMID30407441
PMCPMC6189758
OpenAlexW2338705706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.