Evidence map›Paper›PMID 30407398›Full record

ReviewMicromachines2016

A Review of Biomedical Centrifugal Microfluidic Platforms.

Minghui Tang, Guanghui Wang, Siu-Kai Kong, Ho-Pui Ho

Abstract readReview
In one paragraph

Review in Micromachines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A passive flow microreactor for urine creatinine test.Microsystems & nanoengineering · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minghui TangDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, China. mhtang@ee.cuhk.edu.hk.
Guanghui WangInstitute of Optical Communication Engineering, Nanjing University, Jiangsu 210009, China. wangguanghui@nju.edu.cn.
Siu-Kai KongSchool of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China. skkong@cuhk.edu.hk.
Ho-Pui HoDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, China. hpho@ee.cuhk.edu.hk.

Funding

Hong Kong Medical and Health Research Fund 02130266Hong Kong Research Grants Council 412613Hong Kong Research Grants Council AoE/P-02/12Hong Kong Research Grants Council CUHK1/CRF/12G
6 · The paper itself

Abstract

Centrifugal microfluidic or lab-on-a-disc platforms have many advantages over other microfluidic systems. These advantages include a minimal amount of instrumentation, the efficient removal of any disturbing bubbles or residual volumes, and inherently available density-based sample transportation and separation. Centrifugal microfluidic devices applied to biomedical analysis and point-of-care diagnostics have been extensively promoted recently. This paper presents an up-to-date overview of these devices. The development of biomedical centrifugal microfluidic platforms essentially covers two categories: (i) unit operations that perform specific functionalities, and (ii) systems that aim to address certain biomedical applications. With the aim to provide a comprehensive representation of current development in this field, this review summarizes progress in both categories. The advanced unit operations implemented for biological processing include mixing, valving, switching, metering and sequential loading. Depending on the type of sample to be used in the system, biomedical applications are classified into four groups: nucleic acid analysis, blood analysis, immunoassays, and other biomedical applications. Our overview of advanced unit operations also includes the basic concepts and mechanisms involved in centrifugal microfluidics, while on the other hand an outline on reported applications clarifies how an assembly of unit operations enables efficient implementation of various types of complex assays. Lastly, challenges and potential for future development of biomedical centrifugal microfluidic devices are discussed.

Indexed as

biomedicalbloodcellscentrifugal microfluidicsimmunoassayslab-on-a-disc (LOAD)nucleic acidpoint-of-care diagnostics

Identifiers

PMID30407398
PMCPMC6190084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.