ReviewEnvironmental health perspectives2018
A State-of-the-Science Review of Mercury Biomarkers in Human Populations Worldwide between 2000 and 2018.
Review in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 5 syntheses or guidelines pooled it, 211 citations in OpenAlex.
- Clinical characteristics, management, and outcomes of diseases caused by mercury overexposure: a systematic review of case reports and case series.Frontiers in public health · 2026Pooled it
- Relationship of prenatal methylmercury exposure and language/verbal function: a meta-analysis.Environmental health : a global access science source · 2025Pooled it
- Re-thinking the link between exposure to mercury and blood pressure.Archives of toxicology · 2025Pooled it
- A Systematic Review of Mercury Exposures from Skin-Lightening Products.Environmental health perspectives · 2022Pooled it
- Systematic Review and Meta-Analysis of Mercury Exposure among Populations and Environments in Contact with Electronic Waste.International journal of environmental research and public health · 2022Pooled it
- Chelation treatment in a novel sub-toxic multi-metal model in rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Human Mercury Biomonitoring Under the Minamata Convention: Blood, Urine, Hair, and Tissue Biomarkers (2000-2026).Biological trace element research · 2026Review
- Sperm-Associated Mercury Species Levels Determine Its Impairment: Evidence from Paired Analyses of Whole Semen and Seminal Plasma.Biological trace element research · 2026Article
- Prenatal urinary biomarkers of metal and metalloid exposure and child neurodevelopmental outcomes in Puerto Rico.Environmental research · 2026Article
- Distinct demethylation pathways of rice- and fish-derived methylmercury in pregnant women revealed by compound-specific isotope analysis.Eco-Environment & Health · 2026Article
- Environmental metal exposure and autism spectrum disorder: spatial analysis of exposure patterns and associated risk among children in Alabama.Environmental science and pollution research international · 2026Article
- Quantifying Depuration of Methylmercury from Fish Consumption by Travelers.Environment & health (Washington, D.C.) · 2026Article
- Human biomonitoring in support of the Minamata Convention: a case of phasing out dental amalgam.Environmental health : a global access science source · 2026Article
- Genetic susceptibility to mercury in the amazon: A cross-sectional approach to snps analyses in exposed riverine populations.Genetics and molecular biology · 2026Article
- Blood and cerebrospinal fluid metallomics uncover mercury, chromium, and iron alterations inJournal of Parkinson's disease · 2025Article
- Article
- Which prenatal biomarker is most appropriate for methylmercury dose-response for neurodevelopmental effects?Journal of toxicology and environmental health. Part B, Critical reviews · 2025Review
- A cross-sectional study assessing mercury exposure and poisoning among workers in informal gold mines in French Guiana.BMJ open · 2025Article
- Chemical Prioritisation for Human Biomonitoring in Ireland: A Synergy of Global Frameworks and Local Perspectives.Toxics · 2025Article
- Elevated methylmercury in Arctic rain and aerosol linked to air-sea exchange of dimethylmercury.Science advances · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
Abstract
backgroundThe Minamata Convention on Mercury provided a mandate for action against global mercury pollution. However, our knowledge of mercury exposures is limited because there are many regions and subpopulations with little or no data.
objectiveWe aimed to increase worldwide understanding of human exposures to mercury by collecting, collating, and analyzing mercury concentrations in biomarker samples reported in the published scientific literature.
methodA systematic search of the peer-reviewed scientific literature was performed using three databases. A priori search strategy, eligibility criteria, and data extraction steps were used to identify relevant studies.
resultsWe collected 424,858 mercury biomarker measurements from 335,991 individuals represented in 312 articles from 75 countries. General background populations with insignificant exposures have blood, hair, and urine mercury levels that generally fall under [Formula: see text], [Formula: see text], and [Formula: see text], respectively. We identified four populations of concern:
conclusionsThis review suggests that all populations worldwide are exposed to some amount of mercury and that there is great variability in exposures within and across countries and regions. There remain many geographic regions and subpopulations with limited data, thus hindering evidence-based decision making. This type of information is critical in helping understand exposures, particularly in light of certain stipulations in the Minamata Convention on Mercury. https://doi.org/10.1289/EHP3904.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.