ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019
Synovitis following anterior cruciate ligament reconstruction using the LARS device.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- A systematic review of distal medial collateral ligament Stener-like lesion: Good clinical and functional outcomes of surgical treatment.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Suture tape augmentation, a novel application of synthetic materials in anterior cruciate ligament reconstruction: A systematic review.Frontiers in bioengineering and biotechnology · 2022Pooled it
- Trial
- Patient-reported outcomes after anterior cruciate ligament reconstruction with the JewelACL synthetic ligament: Multicenter study of at least 9 years follow-up.Journal of experimental orthopaedics · 2026Review
- Effectiveness of synthetic vs. autologous ligaments in anterior cruciate ligament reconstruction with remnant preservation: a retrospective cohort study.Frontiers in sports and active living · 2026Article
- No Difference in Clinical Outcomes Between Concomitant Anterior and Posterior Cruciate Ligament Reconstruction With and Without Independent Suture Tape Augmentation.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- 8-11 year results of LARS augmented hamstring in anterior cruciate ligament reconstruction surgery: Incidence of synovitis and failures.Journal of orthopaedics · 2025Article
- Chronic reactive synovitis in patients undergoing ACL reconstruction and augmentation with tape-type sutures.Journal of clinical orthopaedics and trauma · 2025Article
- Black phosphorus-doped silk fibroin coating improves osteogenesis for ameliorative graft-bone healing of polyethylene terephthalate artificial ligaments.Frontiers in bioengineering and biotechnology · 2025Article
- Anterior Cruciate Ligament Reconstruction with LARS Synthetic Ligament: Outcomes and Failures.Journal of clinical medicine · 2024Article
- Synthetic Grafts in Anterior Cruciate Ligament Reconstruction Surgery in Professional Female Handball Players-A Viable Option?Diagnostics (Basel, Switzerland) · 2024Article
- Anatomic Double-Bundle Transtibial Anterior Cruciate Ligament Reconstruction With Ligament Advanced Reinforcement System.Arthroscopy techniques · 2024Article
- Clinical Research Progress of Internal Brace Ligament Augmentation Technique in Knee Ligament Injury Repair and Reconstruction: A Narrative Review.Journal of clinical medicine · 2023Review
- Reconstruction of chronic anterior cruciate ligament rupture using the ligament advanced reinforcement system artificial ligament-comparisons between patients over 50 years and under 50 years.Annals of translational medicine · 2023Article
- Anterior Cruciate Ligament Reconstruction with Quadrupled Semitendinosus Graft or Synthetic Ligament: Knee Stability and Clinical Outcomes at Three Years Follow-Up.Advances in orthopedics · 2023Article
- Risk Factors Affecting the Survival Rate of Collagen Meniscal Implant for Partial Meniscal Deficiency: An Analysis of 156 Consecutive Cases at a Mean 10 Years of Follow-up.The American journal of sports medicine · 2022Article
- Satisfactory patient-reported outcomes at 5 years following primary repair with suture tape augmentation for proximal anterior cruciate ligament tears.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Posterior cruciate ligament repair with suture tape augmentation: a case series with minimum 2-year follow-up.Journal of experimental orthopaedics · 2021Article
- Massive Chondrolysis and Joint Destruction after Artificial Anterior Cruciate Ligament Repair.Case reports in orthopedics · 2021Article
- Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft-Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk-Collagen Scaffold.Stem cells international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Ligament Augmentation and Reconstruction System (LARS
methodsA retrospective analysis was performed of a single surgeon's series of 12 patients that underwent second-look arthroscopic surgery following primary LARS ACL surgery for indications including mechanical symptoms (meniscal tears/cyclops lesions/chondral flaps) and/or symptomatic instability secondary to LARS failure. In all cases an examination under anaesthesia (EUA) was performed, and a qualitative assessment of the synovium was carried out and graded as normal, reactive or inflammatory. A synovial biopsy was performed in all knees with visible evidence of synovitis and in all cases of LARS failure.
resultsThe second-look arthroscopy was performed at a mean of 23 months (7-66) after the index surgery. In 6 (50%) knees the LARS device had failed necessitating removal and revision ACL reconstruction, while in the remaining 6 knees the LARS was still intact. Arthroscopic evaluation of the synovium revealed a normal appearance in 8 knees (67%) and reactive synovitis in 4 knees (23%); of these 4 knees, one had an intact LARS device and 3 had failed LARS. Histological examination from these 4 knees and the 3 knees with graft failures without visible synovitis revealed chronic hypertrophic synovitis (moderate 2, mild 5) in all cases with rare giant cells, consistent with a reaction to foreign body material.
conclusionsForeign body synovitis is a common finding in our series of patients undergoing a repeat arthroscopy following a LARS ACL reconstruction. The histological diagnosis of synovitis was more frequently encountered than an arthroscopic appearance of synovitis. Whilst the results of this case series cannot support a direct causative link between LARS failure and the development of synovitis, this study highlights the need to remain vigilant about the risk of reactive synovitis following LARS ACL reconstruction due to exposure of the knee to foreign body material. LEVEL OF EVIDENCE: Level IV, case series.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.