ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2019
Zinc ameliorates intestinal barrier dysfunctions in shigellosis by reinstating claudin-2 and -4 on the membranes.
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Article in American journal of physiology. Gastrointestinal and liver physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Therapeutic zinc targets dysregulated GC-C signaling and restores ileal defects in a preclinical model of familial diarrheal disease.American journal of physiology. Gastrointestinal and liver physiology · 2026Article
- Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based Study.International journal of molecular sciences · 2025Article
- Deletion of metal transporter Zip14 reduces major histocompatibility complex II expression in murine small intestinal epithelial cells.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Micronutrients at Supplemental Levels, Tight Junctions and Epithelial Barrier Function: A Narrative Review.International journal of molecular sciences · 2024Review
- Review
- Zinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4/NF-κB pathway in meat ducks.Journal of animal science and biotechnology · 2024Article
- Protective effect of zinc gluconate on intestinal mucosal barrier injury in antibiotics and LPS-induced mice.Frontiers in microbiology · 2024Article
- Development and Characterization of an In Vitro Intestinal Model Including Extracellular Matrix and Macrovascular Endothelium.Molecular pharmaceutics · 2023Article
- Enterocyte-specific deletion of metal transporter Zip14 (Slc39a14) alters intestinal homeostasis through epigenetic mechanisms.American journal of physiology. Gastrointestinal and liver physiology · 2023Article
- Relevance of biomarkers indicating gut damage and microbial translocation in people living with HIV.Frontiers in immunology · 2023Review
- Micronutrient Improvement of Epithelial Barrier Function in Various Disease States: A Case for Adjuvant Therapy.International journal of molecular sciences · 2022Review
- Effects of Dietary Nutrients on Fatty Liver Disease Associated With Metabolic Dysfunction (MAFLD): Based on the Intestinal-Hepatic Axis.Frontiers in nutrition · 2022Review
- Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity.World journal of gastroenterology · 2021Article
- Gut Microbiota as a Mediator of Essential and Toxic Effects of Zinc in the Intestines and Other Tissues.International journal of molecular sciences · 2021Review
- Tight Junctions as a Key for Pathogens Invasion in Intestinal Epithelial Cells.International journal of molecular sciences · 2021Review
- Intestinal TMEM16A control luminal chloride secretion in a NHERF1 dependent manner.Biochemistry and biophysics reports · 2021Article
- Role of Nuclear Claudin-4 in Renal Cell Carcinoma.International journal of molecular sciences · 2020Article
- A Dual Zinc plus Arginine formulation attenuates the pathogenic properties ofJournal of oral microbiology · 2020Article
- The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion.Nature communications · 2020Article
- Baitouweng Decoction Ameliorates Ulcerative Colitis in Mice Partially Attributed to Regulating Th17/Treg Balance and Restoring Intestinal Epithelial Barrier.Frontiers in pharmacology · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Paramita SarkarMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Tultul SahaMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Irshad Ali SheikhMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Subhra ChakrabortyDepartment of International Health, John Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Joydeep AounMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Manoj Kumar ChakrabartiMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Vazhaikkurichi M RajendranDepartment of Biochemistry, West Virginia University School of Medicine , Morgantown, West Virginia.
Nadia A AmeenDepartment of Pediatrics/Gastroenterology and Hepatology, Cellular and Molecular Physiology, Yale School of Medicine , New Haven, Connecticut.
Shanta DuttaBacteriology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
Kazi Mirajul HoqueMolecular Pathophysiology Division, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata , India.
National Institute of Cholera and Enteric Diseases · INJohns Hopkins University · USWest Virginia University · USYale University · US
Funding
Role of BK Channels in K+-driven Colonic Water Secretion in Health and DiseaseR01DK104791 · NIDDK · WEST VIRGINIA UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 2015 to 2019
$1.7MAldosterone Activation of Trans-epithelial Iron Absorption in Human ColonR21DK112085 · NIDDK · WEST VIRGINIA UNIVERSITY · PI RAJENDRAN, VAZHAIKKURICHI M. · 2018 to 2019
$404kNIDDK NIH HHS R01 DK104791NIDDK NIH HHS R21 DK112085
Abstract
Whether zinc (Zn
Indexed as
AnimalsClaudin-2Claudin-4Epithelial CellsIntestinal DiseasesMaleMice, Inbred BALB CMice, Inbred C57BLMitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesPermeabilityTight JunctionsZincClaudin-2Claudin-4Mitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesZincclaudindiarrheaintestinal inflammationtight junction
Identifiers
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Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.