ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020
Automated dynamic motion correction using normalized gradient fields for
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Reducing motion-correction-induced variability inJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Trial
- Feasibility of Quantitative Myocardial Perfusion with CZT SPECT and SPECT/CT: Current Limitations and Recommendations for Future Improvements.Current cardiology reports · 2026Review
- Dynamic frame-by-frame motion correction forEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Data-Driven Motion Correction Algorithm: Validation in [Journal of clinical medicine · 2026Article
- Inter-Software Reproducibility of Quantitative Values of Myocardial Blood Flow and Coronary Flow Reserve Acquired by [Diagnostics (Basel, Switzerland) · 2025Article
- TAI-GAN: A Temporally and Anatomically Informed Generative Adversarial Network for early-to-late frame conversion in dynamic cardiac PET inter-frame motion correction.Medical image analysis · 2024Article
- Downward myocardial creep during stress PET imaging is inversely associated with mortality.European journal of nuclear medicine and molecular imaging · 2024Article
- Integrated myocardial flow reserve (iMFR) assessment: diffuse atherosclerosis and microvascular dysfunction are more strongly associated with mortality than focally impaired perfusion.European journal of nuclear medicine and molecular imaging · 2023Article
- Automated dynamic motion correction improves repeatability and reproducibility of myocardial blood flow quantification with rubidium-82 PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Precision of Myocardial Blood Flow and Flow Reserve Measurement During CZT SPECT Perfusion Imaging Processing: Intra- and Interobserver Variability.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- The prevalence of image degradation due to motion in rest-stress rubidium-82 imaging on a SiPM PET-CT system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Activity regimes for 82Rb cardiac PET: Effects on absolute MBF and MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Test-retest repeatability and software reproducibility of myocardial flow measurements using rest/adenosine stress Rubidium-82 PET/CT with and without motion correction in healthy young volunteers.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Automatic Inter-Frame Patient Motion Correction for Dynamic Cardiac PET Using Deep Learning.IEEE transactions on medical imaging · 2021Article
- More evidence for adequate test-retest repeatability of myocardial blood flow quantification withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Dynamic cardiac PET motion correction using 3D normalized gradient fields in patients and phantom simulations.Medical physics · 2021Article
- Assessment of motion correction in dynamic rubidium-82 cardiac PET with and without frame-by-frame adjustment of attenuation maps for calculation of myocardial blood flow.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Optimizing accuracy and precision with motion correction of PET myocardial blood flow measurements.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Patient motion correction for dynamic cardiac PET: Current status and challenges.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPatient motion can lead to misalignment of left ventricular (LV) volumes-of-interest (VOIs) and subsequently inaccurate quantification of myocardial blood flow (MBF) and flow reserve (MFR) from dynamic PET myocardial perfusion images. We aimed to develop an image-based 3D-automated motion-correction algorithm that corrects the full dynamic sequence for translational motion, especially in the early blood phase frames (~ first minute) where the injected tracer activity is transitioning from the blood pool to the myocardium and where conventional image registration algorithms have had limited success.
methodsWe studied 225 consecutive patients who underwent dynamic rest/stress rubidium-82 chloride (
resultsThe automated motion-correction shifts were within 5 mm of the manual motion-correction shifts across the entire sequence. The automated and manual motion-correction global MBF values had excellent linear agreement (R = 0.99, y = 0.97x + 0.06). Uncorrected flows outside of the limits of agreement with the manual motion-corrected flows were brought into agreement in 90% of the cases for global MBF and in 87% of the cases for global MFR. The limits of agreement for stress MBF were also reduced twofold globally and by fourfold in the RCA territory.
conclusionsAn image-based, automated motion-correction algorithm for dynamic PET across the entire dynamic sequence using normalized gradient fields matched the results of manual motion correction in reducing bias and variance in MBF and MFR, particularly in the RCA territory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.