Evidence map›Paper›PMID 30406311›Full record

ArticleEuropean radiology2019

Predictive value of sarcopenia and visceral obesity for postoperative pancreatic fistula after pancreaticoduodenectomy analyzed on clinically acquired CT and MRI.

Minji Jang, Hyung Woo Park, Jimi Huh, Jong Hwa Lee, Yoong Ki Jeong, Yang Won Nah, Jisuk Park, Kyung Won Kim

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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Minji JangDepartment of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Hyung Woo ParkDepartment of Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Jimi HuhDepartment of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea. jimihuh.rad@gmail.com.
Jong Hwa LeeDepartment of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Yoong Ki JeongDepartment of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Yang Won NahDepartment of Surgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Jisuk ParkDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Kyung Won KimDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Ulsan College · KRUlsan University Hospital · KRUniversity of Ulsan · KRAsan Medical Center · KR

Funding

Guerbet No. GK-XTX-2017-34Korea Health Industry Development Institute HI18C1216
6 · The paper itself

Abstract

objectiveTo evaluate predictive values of sarcopenia and visceral obesity measured from preoperative CT/MRIs for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy in patients with periampullary malignancies.

methodsFrom the prospectively constructed surgical registry, we included adult patients treated with pancreaticoduodenectomy. Based on CT/MRIs, body morphometric analysis was performed to evaluate the visceral obesity and sarcopenia, based on the areas of visceral fat and skeletal muscle measured at the L3 vertebrae level. We retrieved various perioperative factors from registry. As outcomes of postoperative complications, we evaluated POPF and major complications based on the Clavien-Dindo classification. Multivariate logistic regression analyses were performed.

resultsFrom a total of 284 patients (163 males, 121 females) who met the inclusion/exclusion criteria, POPF, major complications, and 60-day mortality occurred in 52 (18.3%), 34 (12.0%), and 6 (2.1%), respectively. Sarcopenia and visceral obesity were noted in 123 (75.5%) and 66 (40.5%) of men and 68 (56.2%) and 53 (43.8%) of women, respectively. Combination of sarcopenia and obesity (sarcopenic obesity) was noted in 31.9% (52/163) of men and in 26.4% (32/121) of women. In multivariate logistic regression analyses, sarcopenic obesity was the only independent predictor for POPF (OR 2.65, 95% CI 1.43-4.93), and the vascular resection during pancreaticoduodenectomy was the only independent predictor for severe complications (OR 3.75, 95% CI 1.61-8.70).

conclusionSarcopenic obesity might be highly predictive for POPF. Body morphometric analysis in preoperative CT/MRI combined with assessment of perioperative clinical features may help to identify high-risk patients and determine perioperative management strategies. KEY POINTS: • Sarcopenic obesity might be predictive for postoperative pancreatic fistula after pancreaticoduodenectomy. • The vascular resection during pancreaticoduodenectomy might be predictive of major complications. • Body morphometric analysis might be helpful for identifying high-risk patients.

Indexed as

Postoperative ComplicationsAdultAgedFemaleHumansIntra-Abdominal FatMagnetic Resonance ImagingMaleMiddle AgedMuscle, SkeletalObesity, AbdominalPancreatic FistulaPancreaticoduodenectomyPredictive Value of TestsPreoperative PeriodRisk FactorsMuscle weaknessPancreaticoduodenectomyPostoperative complicationsSarcopeniaTreatment outcome

Identifiers

PMID30406311
OpenAlexW2900416199

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.