ArticleSocial psychiatry and psychiatric epidemiology2019
Trends in prescriptions for sedative-hypnotics among Korean adults: a nationwide prescription database study for 2011-2015.
Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Pooled it
- Efficacy and safety of TCM Yangxin Anshen Therapy for insomnia: A systematic review and meta-analysis.Medicine · 2020Pooled it
- Association between sedative prescriptions after hospital discharge and falls and other adverse events in older adults: a population-based cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Trends in Sedative-Hypnotic Prescription Among Insomnia Patients: A Nationwide Cohort Study From 2010 to 2022 in Korea.Journal of Korean medical science · 2026Article
- Article
- Trends in the use and nonmedical use of sedatives-hypnotics in the population aged 12 to 64 years in Taiwan: a comparative analysis of the national surveys in 2014 and 2018.BMC public health · 2024Article
- Development of a Web Application for Simulating Plasma Drug Concentrations in Patients with Zolpidem Intoxication.Pharmaceutics · 2024Article
- Medication-Seeking Behaviors and Correlated Characteristics of Zolpidem Users in Taiwan-A Shared Patient Network Analysis.Healthcare (Basel, Switzerland) · 2024Article
- Association Between Persistent Treatment of Alzheimer's Dementia and Osteoporosis Using a Common Data Model.Dementia and neurocognitive disorders · 2023Article
- Benzodiazepines in complex biological matrices: Recent updates on pretreatment and detection methods.Journal of pharmaceutical analysis · 2023Review
- Hypnotic prescription trends and patterns for the treatment of insomnia in Japan: analysis of a nationwide Japanese claims database.BMC psychiatry · 2023Article
- Physicians' attitudes toward hypnotics for insomnia: A questionnaire-based study.Frontiers in psychiatry · 2023Article
- Long-term methylphenidate use for children and adolescents with attention deficit hyperactivity disorder and risk for depression, conduct disorder, and psychotic disorder: a nationwide longitudinal cohort study in South Korea.Child and adolescent psychiatry and mental health · 2022Article
- Transcutaneous Vagus Nerve Stimulation Could Improve the Effective Rate on the Quality of Sleep in the Treatment of Primary Insomnia: A Randomized Control Trial.Brain sciences · 2022Article
- Trends in Prescriptions for Insomnia in a Province in China Between 2015 and 2019.Frontiers in psychiatry · 2022Article
- Pregnancy and Neonatal Outcomes After Exposure to Alprazolam in Pregnancy.Frontiers in pharmacology · 2022Article
- Analysis of Medical Services for Insomnia in Korea: A Retrospective, Cross-Sectional Study Using the Health Insurance Review and Assessment Claims Data.Healthcare (Basel, Switzerland) · 2021Article
- Effect of CYP3A4 metabolism on sex differences in the pharmacokinetics and pharmacodynamics of zolpidem.Scientific reports · 2021Article
- Electronic dashboard-based remote glycemic management program reduces length of stay and readmission rate among hospitalized adults.Journal of diabetes investigation · 2021Article
- Prescribing Pattern of Hypnotic Medications in Patients Initiating Treatment at Japanese Hospitals: A Nationwide, Retrospective, Longitudinal, Observational Study Using a Claims Database.Drugs - real world outcomes · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
purposeThis study investigated prescriptions for sedative-hypnotics via data obtained from the Health Insurance Review and Assessment (HIRA) service.
methodsData on sedative-hypnotic prescriptions from the HIRA service of the Republic of Korea were analyzed from 2011 to 2015. We included prescriptions for subjects > 18 years of age from hospitals and community healthcare centers. In addition, subgroup analyses with a subsample restricted to prescriptions from patients with diagnostic codes F510 (nonorganic insomnia) or G470 (insomnia) were performed. After analyzing the number of prescriptions by individual pharmacy items, the prescription codes were grouped as: (1) benzodiazepines; (2) non-benzodiazepines, including zolpidem; (3) antidepressants; and (4) antipsychotics. We calculated the monthly percent change in the number of prescriptions by drug group using Joinpoint regression.
resultsAmong the sedative-hypnotic groups, benzodiazepines were the most commonly prescribed drugs in Korea during the study period. As a single sedative-hypnotic item, zolpidem was the most frequently prescribed medication for patients with insomnia. Prescriptions for all groups of sedative-hypnotics increased significantly during the study period. When stratified by age group, antipsychotic prescriptions increased significantly by 0.19-0.21% per month among men and women aged 50-59 years and > 70 years. Prescriptions for antidepressants in 30-39-year-old men increased significantly by 0.20%.
conclusionsBenzodiazepine prescriptions as well as those for antipsychotics and antidepressants to treat insomnia increased during 2011-2015 in Korea. Monitoring the use of sedative-hypnotics at the national level is necessary, especially in the elderly population.
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