Evidence map›Paper›PMID 30406186›Full record

ArticleeNeuro

Maternal Immune Activation Alters Adult Behavior, Gut Microbiome and Juvenile Brain Oscillations in Ferrets.

Yuhui Li, Supritha R Dugyala, Travis S Ptacek, John H Gilmore, Flavio Frohlich

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Maternal Immune Activation during Pregnancy Alters Postnatal Brain Growth and Cognitive Development in Nonhuman Primate Offspring.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  10. Article
  11. Article
  12. The Ferret as a Model System for Neocortex Development and Evolution.Frontiers in cell and developmental biology · 2021
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuhui LiDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Supritha R DugyalaDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Travis S PtacekNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
John H GilmoreDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-0939-6764
Flavio FrohlichDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-3724-5621
University of North Carolina at Chapel Hill · US

Funding

Targeting Cortical Dynamics: Rational Design of Individualized Brain StimulationR01MH101547 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FROHLICH, FLAVIO · 2013 to 2017
$2.2M
NIMH NIH HHS R01 MH101547
6 · The paper itself

Abstract

Maternal immune activation (MIA) has been identified as a causal factor in psychiatric disorders by epidemiological studies in humans and mechanistic studies in rodent models. Addressing this gap in species between mice and human will accelerate the understanding of the role of MIA in the etiology of psychiatric disorders. Here, we provide the first study of MIA in the ferret (

Indexed as

AgingAnimalsBehavior, AnimalBrainDisease Models, AnimalFemaleFerretsGastrointestinal MicrobiomeMental DisordersPregnancyPrenatal Exposure Delayed EffectsSocial BehaviorVisual Cortexbehaviordevelopmental disordersferretsmaternal immune activationmicrobiomeoscillations

Identifiers

PMID30406186
PMCPMC6220580
OpenAlexW2892746257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.