Evidence map›Paper›PMID 30406081›Full record

ReviewFrontiers in chemistry2018

Functional Hydrogels With Tunable Structures and Properties for Tissue Engineering Applications.

Xiaomeng Li, Qingqing Sun, Qian Li, Naoki Kawazoe, Guoping Chen

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed.

  1. Article
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  5. Review
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  12. Review 3D-Printed hydrogels for tissue engineering: a review.Frontiers in bioengineering and biotechnology · 2026
    Review
  13. Dendrimers-based Hydrogels and Nanogels for Drug Delivery.Current pharmaceutical biotechnology · 2026
    Review
  14. Article
  15. Review
  16. Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Article

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaomeng LiSchool of Mechanics and Engineering Science, Zhengzhou University, Zhengzhou, China.
Qingqing SunCenter for Functional Sensor and Actuator, National Institute for Materials Science, Tsukuba, Japan.
Qian LiSchool of Mechanics and Engineering Science, Zhengzhou University, Zhengzhou, China.
Naoki KawazoeResearch Center for Functional Materials, National Institute for Materials Science, Tsukuba, Japan.
Guoping ChenResearch Center for Functional Materials, National Institute for Materials Science, Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering (TE) has been used as an attractive and efficient process to restore the original tissue structures and functions through the combination of biodegradable scaffolds, seeded cells, and biological factors. As a unique type of scaffolds, hydrogels have been frequently used for TE because of their similar 3D structures to the native extracellular matrix (ECM), as well as their tunable biochemical and biophysical properties to control cell functions such as cell adhesion, migration, proliferation, and differentiation. Various types of hydrogels have been prepared from naturally derived biomaterials, synthetic polymers, or their combination, showing their promise in TE. This review summarizes the very recent progress of hydrogels used for TE applications. The strategies for tuning biophysical and biochemical properties, and structures of hydrogels are first introduced. Their influences on cell functions and promotive effects on tissue regeneration are then highlighted.

Indexed as

chemical propertiesfunctional hydrogelsmicrostructuresphysical propertiestissue engineering

Identifiers

PMID30406081
PMCPMC6204355

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.