Evidence map›Paper›PMID 30406000›Full record

ArticleClinical nephrology. Case studies2018

Successful recovery of associated interstitial nephritis and focal segmental glomerulosclerosis in patients with HCV and HIV treated with sofosbuvir and daclatasvir and revision of literature.

Michele Mirabella, Lucia Taramasso, Laura Ambra Nicolini, Rodolfo Russo, Claudio Viscoli, Antonio Di Biagio

Open access · greenAbstract readCase Reports
In one paragraph

Article in Clinical nephrology. Case studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Michele MirabellaInfectious Diseases Unit.
Lucia TaramassoInfectious Diseases Unit.
Laura Ambra NicoliniInfectious Diseases Unit.
Rodolfo RussoNephrology Unit, and.
Claudio ViscoliInfectious Diseases Unit.
Antonio Di BiagioInfectious Diseases Unit, Ospedale Policlinico San Martino, Genoa, Italy.
Ospedale Policlinico San Martino · ITPediatric Nephrology of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report, we describe the coexistence of two rare and debated complications of hepatitis C virus (HCV) infection: interstitial nephritis, with associated focal glomerulosclerosis, and autoimmune hepatitis, in a 55-year-old HIV/HCV-coinfected woman. The patient was treated for the immune-mediated manifestations with mycophenolate mofetil, which she continued for 9 years, as symptoms relapsed at every attempt to discontinue immunosuppression. The patient finally cleared HCV infection thanks to new direct-acting agents and could discontinue immunosuppressive therapy maintaining stable conditions and laboratory parameters after 24-weeks follow-up.

Indexed as

focal segmental glomerulosclerosisHIV/HCV coinfectionkidney diseasemycophenolate mofetilsustained viral response

Identifiers

PMID30406000
PMCPMC6218875
OpenAlexW2898521580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.