Evidence map›Paper›PMID 30405965›Full record

ArticleTranslational vision science & technology2018

Depth-Based, Motion-Stabilized Colorization of Microscope-Integrated Optical Coherence Tomography Volumes for Microscope-Independent Microsurgery.

Isaac D Bleicher, Moseph Jackson-Atogi, Christian Viehland, Hesham Gabr, Joseph A Izatt, Cynthia A Toth

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01588041 (Intraoperative OCT Guidance of Intraocular Surgery), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01588041 completednot on this map

Intraoperative OCT Guidance of Intraocular Surgery

TypeobservationalSponsorDuke UniversityRan2009 to 2018Enrolled269ConditionsEye Manifestations
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  2. Article
  3. Article
  4. Processing-Aware Real-Time Rendering for Optimized Tissue Visualization in Intraoperative 4D OCT.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020
    Article
  5. Article
  6. Three-dimensional pattern of extraretinal neovascular development in retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Isaac D BleicherDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Moseph Jackson-AtogiDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Christian ViehlandDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Hesham GabrDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Joseph A IzattDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Cynthia A TothDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Duke University · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Intraoperative OCT Guidance of Intraocular SurgeryR01EY023039 · NEI · DUKE UNIVERSITY · PI IZATT, JOSEPH A, TOTH, CYNTHIA ANN · 2013 to 2016
$3.9M
NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY023039
6 · The paper itself

Abstract

purposeWe develop and assess the impact of depth-based, motion-stabilized colorization (color) of microscope-integrated optical coherence tomography (MIOCT) volumes on microsurgical performance and ability to interpret surgical volumes.

methodsColor was applied in real-time as gradients indicating axial position and stabilized based on calculated center of mass. In a test comparing colorization versus grayscale visualizations of prerecorded intraoperative volumes from human surgery, ophthalmologists (

resultsIn intraoperative volume testing, colorization improved ability to differentiate membrane from retina (

conclusionsDepth-based colorization enables effective identification of retinal membranes and tissue deformation. In microsurgical skill testing, it improves user efficiency, and confidence in microscope-independent, OCT-guided model surgical maneuvers. TRANSLATIONAL RELEVANCE: Novel depth-based colorization and stabilization technology improves the use of intraoperative MIOCT.

Indexed as

intraoperative imagingmicrosurgeryophthalmic surgeryoptical coherence tomographyvisualization

Identifiers

PMID30405965
PMCPMC6218157
OpenAlexW2898800262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.