Evidence map›Paper›PMID 30405640›Full record

ArticleFrontiers in immunology2018

Ultrasensitive Quantification of Cytokine Proteins in Single Lymphocytes From Human Blood Following

Ankit Saxena, Pradeep K Dagur, Alisha Desai, John Philip McCoy

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ankit SaxenaNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
Pradeep K DagurNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
Alisha DesaiNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.
John Philip McCoyNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.

Funding

Flow Cytometry Core FacilityZICHL005905 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DAGUR, PRADEEP · 2009 to 2025
$32.3M
6 · The paper itself

Abstract

In this study we demonstrate the feasibility of direct, quantitative measurement of cytokine proteins in single human CD8 lymphocytes from fresh peripheral blood of healthy donors following a brief

Indexed as

Blood CellsCD8-Positive T-LymphocytesCells, CulturedFlow CytometryHumansImmunoassayInterferon-gammaSensitivity and SpecificitySingle-Cell AnalysisTumor Necrosis Factor-alphaInterferon-gammaTumor Necrosis Factor-alphaflow cytometryIFN-γSiMoAT cellTNF-α

Identifiers

PMID30405640
PMCPMC6206239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.