Evidence map›Paper›PMID 30405632›Full record

ArticleFrontiers in immunology2018

Phenotype, Polyfunctionality, and Antiviral Activity of

Jimena Salido, María Julia Ruiz, César Trifone, María Inés Figueroa, María Paula Caruso, María Magdalena Gherardi, Omar Sued, Horacio Salomón, Natalia Laufer, Yanina Ghiglione and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. CD8Heliyon · 2024
    Article
  4. Memory stem CD8Frontiers in cellular and infection microbiology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jimena SalidoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
María Julia RuizConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
César TrifoneConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
María Inés FigueroaFundación Huésped, Buenos Aires, Argentina.
María Paula CarusoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
María Magdalena GherardiConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
Omar SuedFundación Huésped, Buenos Aires, Argentina.
Horacio SalomónConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
Natalia LauferConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
Yanina GhiglioneConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
Gabriela TurkConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad de Buenos Aires, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Buenos Aires, Argentina.
University of Buenos Aires · ARInstituto de Investigaciones Biomédicas en Retrovirus y Sida · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARFundación Huésped · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since anti-HIV treatment cannot cure the infection, many strategies have been proposed to eradicate the viral reservoir, which still remains as a major challenge. The success of some of these strategies will rely on the ability of HIV-specific CD8

Indexed as

Acute DiseaseAnti-Retroviral AgentsCD8-Positive T-LymphocytesCell ProliferationCells, CulturedCytotoxicity, Immunologicgag Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHumansImmunologic MemoryImmunophenotypingLymphocyte Activationnef Gene Products, Human Immunodeficiency VirusPeptide FragmentsProgrammed Cell Death 1 ReceptorAnti-Retroviral Agentsgag Gene Products, Human Immunodeficiency VirusHIV Nef peptide (58-68)nef Gene Products, Human Immunodeficiency VirusPDCD1 protein, humanPeptide FragmentsProgrammed Cell Death 1 Receptorantiviral activityexpanded CD8+ T-cell responseHIV functional curepolyfunctionality and phenotypetime of cART initiation

Identifiers

PMID30405632
PMCPMC6205955
OpenAlexW2897978910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.