Evidence map›Paper›PMID 30405625›Full record

ReviewFrontiers in immunology2018

Human and Murine Evidence for Mechanisms Driving Autoimmune Photosensitivity.

Sonya J Wolf, Shannon N Estadt, Johann E Gudjonsson, J Michelle Kahlenberg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Systemic Lupus Erythematosus Risk: The Role of Environmental Factors.Rheumatic diseases clinics of North America · 2022
    Review
  14. Immunogenetics of Lupus Erythematosus.Advances in experimental medicine and biology · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Skin-kidney crosstalk in SLE.Nature reviews. Rheumatology · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sonya J WolfDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.
Shannon N EstadtDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.
Johann E GudjonssonDepartment of Dermatology, University of Michigan, Ann Arbor, MI, United States.
J Michelle KahlenbergDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · US

Funding

RESEARCH TRAINING IN EXPERIMENTAL IMMUNOPATHOLOGYT32AI007413 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bethany B. Moore · 1993 to 2026
$9.8M
Characterization of Interferon Kappa as a Novel Target in Cutaneous LupusR01AR071384 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joanne Michelle Kahlenberg · 2017 to 2026
$3.6M
Role of IL-13 and the IL-13 Associated rs20541 Risk Variant in the Pathogenesis of PsoriasisR01AR069071 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUDJONSSON, JOHANN ELI · 2015 to 2019
$2.1M
NIAID NIH HHS T32 AI007413NIAMS NIH HHS R01 AR069071NIAMS NIH HHS R01 AR071384
6 · The paper itself

Abstract

Ultraviolet (UV) light is an important environmental trigger for systemic lupus erythematosus (SLE) patients, yet the mechanisms by which UV light impacts disease are not fully known. This review covers evidence in both human and murine systems for the impacts of UV light on DNA damage, apoptosis, autoantigen exposure, cytokine production, inflammatory cell recruitment, and systemic flare induction. In addition, the role of the circadian clock is discussed. Evidence is compared in healthy individuals and SLE patients as well as in wild-type and lupus-prone mice. Further research is needed into the effects of UV light on cutaneous and systemic immune responses to understand how to prevent UV-light mediated lupus flares.

Indexed as

AnimalsApoptosisAutoimmunityCircadian ClocksCytokinesDisease Models, AnimalDNA DamageHumansInflammation MediatorsLupus Erythematosus, SystemicMicePhotosensitivity DisordersUltraviolet RaysCytokinesInflammation Mediatorsapoptosiscytokineslupus (SLE)photosensitivityultraviolet light

Identifiers

PMID30405625
PMCPMC6205973
OpenAlexW2898027492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.