ArticleFrontiers in immunology2018
Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis.
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In one paragraph
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Host blood protein biomarkers to screen for tuberculosis disease: a systematic review and meta-analysis.Journal of clinical microbiology · 2024Pooled it
- Monocytic niches escape T cell surveillance and promote Mycobacterium tuberculosis persistence in lymph nodes.Immunity · 2026Article
- Functional analysis of distinct factors linked to the development of latent to active tuberculosis.Frontiers in cellular and infection microbiology · 2026Review
- The grand escape - how pathogens outsmart the human complement system.Immunobiology · 2025Review
- A bioinformatics-driven approach to identify biomarkers and elucidate the pathogenesis of type 2 diabetes concurrent with pulmonary tuberculosis.Scientific reports · 2025Article
- Dynamic Alterations in DNA Methylation of CD4MedComm · 2025Article
- Single-cell analysis revealsScience advances · 2025Article
- Olink proteomics and lipidomics analysis of serum from patients infected with non-tuberculous mycobacteria and Mycobacterium tuberculosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Increased serum interferon activity in sarcoidosis compared to that in tuberculosis: Implication for diagnosis?Heliyon · 2024Article
- Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis.PLoS pathogens · 2024Article
- Blood transcriptomic signatures for symptomatic tuberculosis in an African multicohort study.The European respiratory journal · 2024Article
- The immune system in Down Syndrome: Autoimmunity and severe infections.Immunological reviews · 2024Review
- C1q and HBHA-specific IL-13 levels as surrogate plasma biomarkers for monitoring tuberculosis treatment efficacy: a cross-sectional cohort study in Paraguay.Frontiers in immunology · 2024Observational
- Comparative Proteomic Analysis of Exosomes Derived from Patients Infected with Non-Tuberculous Mycobacterium andMicroorganisms · 2023Article
- Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q.Scientific reports · 2023Article
- Complement dysregulation and Alzheimer's disease in Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.iScience · 2023Article
- Low serum complement level is associated with higher mortality in tuberculous meningitis: a retrospective cohort study.Encephalitis (Seoul, Korea) · 2023Article
- Complement regulatory proteins: Candidate biomarkers in differentiating tuberculosis pleural effusion.Frontiers in immunology · 2023Article
- Plasma host protein signatures correlating with Mycobacterium tuberculosis activity prior to and during antituberculosis treatment.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 6 institutions in 3 countries.
Rosalie LubbersDepartment of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
Jayne S SutherlandMedical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul, Gambia.
Delia GolettiTranslational Research Unit, Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases, Rome, Italy.
Roelof A de PausDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Coline H M van MoorselDepartment of Pulmonology, St. Antonius Hospital Nieuwegein, Nieuwegein, Netherlands.
Marcel VeltkampDepartment of Pulmonology, St. Antonius Hospital Nieuwegein, Nieuwegein, Netherlands.
Stefan M T VestjensDepartment of Internal Medicine, St. Antonius Hospital Nieuwegein, Nieuwegein, Netherlands.
Willem J W BosDepartment of Internal Medicine, St. Antonius Hospital Nieuwegein, Nieuwegein, Netherlands.
Linda PetroneTranslational Research Unit, Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases, Rome, Italy.
Franca Del NonnoPathology Service, National Institute for Infectious Diseases, Rome, Italy.
Ingeborg M BajemaDepartment of Pathology, Leiden University Medical Center, Leiden, Netherlands.
Karin DijkmanSection of TB Research & Immunology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Frank A W VerreckSection of TB Research & Immunology, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Gerhard WalzlDivision of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Stellenbosch University, Cape Town, South Africa.
Kyra A GeldermanSanquin Diagnostic Services, Amsterdam, Netherlands.
Geert H GroeneveldDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Annemieke GelukDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Simone A JoostenDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Leendert A TrouwDepartment of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLSt. Antonius Ziekenhuis · NLBiomedical Primate Research Centre · NLMRC Unit the Gambia · GMSanquin · NLSouth African Medical Research Council · ZA
Funding
In depth characterization of Mtb specific HLA-E restricted human CD8+ T-cellsR21AI127133 · NIAID · LEIDEN UNIVERSITY MEDICAL CENTER · PI OTTENHOFF, TOM · 2016 to 2017
$281kMedical Research Council MC_U190071468Medical Research Council MC_UP_A900_1122NIAID NIH HHS R21 AI127133
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdolescentAdultAgedAged, 80 and overAnimalsBiomarkersBlood ProteinsComplement C1qDiagnosis, DifferentialFemaleHumansLatent TuberculosisMaleMiddle AgedMycobacterium tuberculosisPneumoniaBiomarkersBlood ProteinsComplement C1qbloodC1qcomplementinfectioninnate immunitymycobacteriumtuberculosis
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.