Evidence map›Paper›PMID 30405620›Full record

ArticleFrontiers in immunology2018

CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Fane F K Mensah, Christopher W Armstrong, Venkat Reddy, Amolak S Bansal, Saul Berkovitz, Maria J Leandro, Geraldine Cambridge

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Fane F K MensahDivision of Medicine, Centre of Rheumatology Research, University College London, London, United Kingdom.
Christopher W ArmstrongBio 21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, VIC, Australia.
Venkat ReddyDivision of Medicine, Centre of Rheumatology Research, University College London, London, United Kingdom.
Amolak S BansalDepartment of Immunology, Epsom and St. Helier University Hospitals NHS Trust, Carshalton, United Kingdom.
Saul BerkovitzChronic Fatigue Service, Royal London Hospital of Integrated Medicine, University College Hospitals NHS Trust, London, United Kingdom.
Maria J LeandroDivision of Medicine, Centre of Rheumatology Research, University College London, London, United Kingdom.
Geraldine CambridgeDivision of Medicine, Centre of Rheumatology Research, University College London, London, United Kingdom.
University College London · GBEpsom and St Helier University Hospitals NHS Trust · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD24 expression on pro-B cells plays a role in B cell selection and development in the bone marrow. We previously detected higher CD24 expression and frequency within IgD+ naïve and memory B cells in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) compared with age-matched healthy controls (HC). Here, we investigated the relationship between CD24 expression and B cell maturation.

Indexed as

Energy MetabolismGene ExpressionAdultBiomarkersB-LymphocytesCD24 AntigenCell DifferentiationFatigue Syndrome, ChronicFemaleGlucoseGlycolysisHumansImmunologic MemoryImmunophenotypingLactic AcidLeukocytes, MononuclearBiomarkersCD24 AntigenCD24 protein, humanGlucoseLactic AcidB cellsCD24ME/CFSmemory B cellsmetabolismpAMPK

Identifiers

PMID30405620
PMCPMC6204382
OpenAlexW2895090555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.