Evidence map›Paper›PMID 30405603›Full record

ArticleFrontiers in immunology2018

Elevated Systemic and Parasite-Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment.

Anuradha Rajamanickam, Saravanan Munisankar, Yukthi Bhootra, Chandrakumar Dolla, Thomas B Nutman, Subash Babu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Anuradha RajamanickamNational Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.
Saravanan MunisankarNational Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.
Yukthi BhootraNational Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.
Chandrakumar DollaNational Institute for Research in Tuberculosis, Chennai, India.
Thomas B NutmanLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Subash BabuNational Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.
International Centers for Excellence in Research · INNational Institute of Allergy and Infectious Diseases · USNational Institute of Research in Tuberculosis · INNational Institutes of Health · US

Funding

India International Center for Excellence in ResearchZIAAI001065 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$19.0M
6 · The paper itself

Abstract

Type III IFNs are important players in immunity to viral and bacterial infections. However, their association with helminth infections has not been examined. To explore the association of Type III IFNs with

Indexed as

AdolescentAdultAgedAnimalsAnthelminticsAntigens, HelminthBiomarkersCytokinesDendritic CellsFemaleHelminthiasisHelminthsHumansInterferonsMaleMiddle AgedAnthelminticsAntigens, HelminthBiomarkersCytokinesInterferonsDC subsetshelminthsIFN lambda-1IFN lambda-2IFN lambda-3Strongyloides stercoralisType III IFNs

Identifiers

PMID30405603
PMCPMC6205947
OpenAlexW2897846458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.