Evidence map›Paper›PMID 30405602›Full record

ArticleFrontiers in immunology2018

Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the

Virginia Santiago, Katayoun Rezvani, Takuya Sekine, Justin Stebbing, Peter Kelleher, Darius Armstrong-James

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
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  8. Article
  9. Aspergillus fumigatus and Aspergillosis in 2019.Clinical microbiology reviews · 2019
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Virginia SantiagoFaculty of Medicine, Imperial College London, National Heart and Lung Institute, London, United Kingdom.
Katayoun RezvaniStem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Centre, Houston, TX, United States.
Takuya SekineKennedy Institute, University of Oxford, Oxford, United Kingdom.
Justin StebbingDepartment of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom.
Peter KelleherFaculty of Medicine, Centre for Immunology and Vaccinology, Imperial College London, London, United Kingdom.
Darius Armstrong-JamesFaculty of Medicine, Imperial College London, National Heart and Lung Institute, London, United Kingdom.
Imperial College London · GBThe University of Texas MD Anderson Cancer Center · USUniversity of Oxford · GB

Funding

Department of Health NIHR-RP-011-053Medical Research Council G0902260
6 · The paper itself

Abstract

Pulmonary aspergillosis is an opportunistic fungal infection affecting immunocompromised individuals. Increasing understanding of natural killer (NK) cell immunobiology has aroused considerable interest around the role of NK cells in pulmonary aspergillosis in the immunocompromised host. Murine studies indicate that NK cells play a critical role in pulmonary clearance of

Indexed as

HyphaeAnimalsAntigen PresentationAspergillosisAspergillus fumigatusCD56 AntigenCell DegranulationCell Line, TumorCell MembraneCytokinesDNA, FungalHumansImmunocompromised HostImmunological SynapsesImmunophenotypingKiller Cells, NaturalCD56 AntigenCytokinesDNA, FungalNCAM1 protein, humanNK Cell Lectin-Like Receptor Subfamily KAspergillus fumigatusfungal diseaseimmunocompromiseleukaemiaNK cells

Identifiers

PMID30405602
PMCPMC6204393
OpenAlexW2897242298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.