Evidence map›Paper›PMID 30405391›Full record

ArticleFrontiers in aging neuroscience2018

Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging.

Gen Shinozaki, Patricia R Braun, Benjamin W Q Hing, Andrew Ratanatharathorn, Mason J Klisares, Gabrielle N Duncan, Sydney S Jellison, Jonathan T Heinzman, Yasunori Nagahama, Liesl Close and 5 more

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
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  14. Observational
  15. Article
  16. Review
  17. Article
  18. Article
  19. Epigenetic Clock: DNA Methylation in Aging.Stem cells international · 2020
    Review
  20. Alteration of the brain methylation landscape following postnatal inflammatory injury in rat pups.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gen ShinozakiDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Patricia R BraunDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, United States.
Benjamin W Q HingDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Andrew RatanatharathornDepartment of Epidemiology, School of Public Health, Columbia University Medical Center, Columbia University, New York, NY, United States.
Mason J KlisaresDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Gabrielle N DuncanDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Sydney S JellisonDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Jonathan T HeinzmanDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Yasunori NagahamaDepartment of Neurosurgery, University of Iowa, Carver College of Medicine, Iowa City, IA, United States.
Liesl CloseDepartment of Neurosurgery, University of Iowa, Carver College of Medicine, Iowa City, IA, United States.
Sayeh SabbaghDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Brian J DlouhyDepartment of Neurosurgery, University of Iowa, Carver College of Medicine, Iowa City, IA, United States.
Matthew A HowardDepartment of Neurosurgery, University of Iowa, Carver College of Medicine, Iowa City, IA, United States.
Hiroto KawasakiDepartment of Neurosurgery, University of Iowa, Carver College of Medicine, Iowa City, IA, United States.
Hyunkeun R ChoDepartment of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, United States.

Funding

SHORT-TERM TRAINING: STUDENTS IN HEALTH PROF. SCHOOLST35HL007485 · NHLBI · UNIVERSITY OF IOWA · PI ROGHAIR, ROBERT D · 1985 to 2019
$4.3M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008629 · NIGMS · UNIVERSITY OF IOWA · PI EBERL, DANIEL F · 1997 to 2021
$4.1M
Epigenetic Investigation of Trauma in PTSD and DepressionK23MH107654 · NIMH · UNIVERSITY OF IOWA · PI SHINOZAKI, GEN · 2015 to 2018
$718k
Flow Cytometry Cell SorterS10OD016199 · OD · UNIVERSITY OF IOWA · PI BALLAS, ZUHAIR K. · 2015 to 2015
$443k
NHLBI NIH HHS T35 HL007485NIGMS NIH HHS T32 GM008629NIH HHS S10 OD016199NIMH NIH HHS K23 MH107654
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingcytokinedeliriumDNA methylationepigeneticstNF-alpha

Identifiers

PMID30405391
PMCPMC6206747

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.