ArticleScientific reports2018
Hyponatremia in children with respiratory infections: a cross-sectional analysis of a cohort of 3938 patients.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Hyponatremia in the neonatal intensive care unit: incidence, risk factors and effect on mortality.BMC pediatrics · 2026Article
- Unusual Presentation of Hyponatremia: Persistent Hiccups.Electrolyte & blood pressure : E & BP · 2025Article
- In-Hospital Risk Factors and Short-Term Outcomes for Subarachnoid Hemorrhage.International journal of general medicine · 2024Article
- Relationship of severity of hyponatremia and adverse outcomes in children visiting the emergency department.Frontiers in pediatrics · 2024Article
- Hyponatremia in babies: a 11-year single-center study.Frontiers in pediatrics · 2024Article
- Thalamic Neuron Resilience during Osmotic Demyelination Syndrome (ODS) Is Revealed by Primary Cilium Outgrowth and ADP-ribosylation factor-like protein 13B Labeling in Axon Initial Segment.International journal of molecular sciences · 2023Article
- Children with mild hyponatremia at the emergency department are at higher risk of hospitalization.BMC pediatrics · 2023Article
- The prevalence and outcomes of hyponatremia in children with COVID-19 and multisystem inflammatory syndrome in children (MIS-C).Frontiers in pediatrics · 2023Article
- Incidence and Severity of Community- and Hospital-Acquired Hyponatremia in Pediatrics.Journal of clinical medicine · 2022Article
- The incidence, hospitalisations and deaths in acutely ill children with dysnatraemias.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- The Differences Between RSV and no RSV Acute Bronchiolitis in Hospitalized Infants: A Cross-Sectional Study.Global pediatric health · 2022Article
- Prevalence, prognostic value, pathophysiology, and management of hyponatraemia in children and adolescents with COVID-19.Acta bio-medica : Atenei Parmensis · 2021Review
- The Utility of Bedside Assessment Tools and Associated Factors to Avoid Antibiotic Overuse in an Urban PICU of a Diarrheal Disease Hospital in Bangladesh.Antibiotics (Basel, Switzerland) · 2021Article
- Hyponatremia in childhood urinary tract infection.European journal of pediatrics · 2021Article
- Usefulness of Kawasaki disease risk scoring systems to the Turkish population.Anatolian journal of cardiology · 2020Article
- Observational
- A New Scoring System for Prediction of Intravenous Immunoglobulin Resistance of Kawasaki Disease in Infants Under 1-Year Old.Frontiers in pediatrics · 2019Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyponatremia can be a life-threatening illness among hospitalized children. The aims of this study were to evaluate the incidence and risk factors of hyponatremia in 3938 children who were admitted to the Cheil General Hospital and Women's Health Care Center with respiratory infections. Clinical data were collected, and multiplex RT-PCR analyses were done for various microorganisms. Hyponatremia was observed in 531 (13.5%) patients. The incidence of hyponatremia differed according to the respiratory tract infection (P < 0.0001) and microorganism (P = 0.001). In children with hyponatremia, the age at admission was significantly older (P < 0.0001), male gender was more frequent (P = 0.019), CRP was higher (P < 0.0001), and coinfection with multiple organisms was more common (P = 0.001) than in children without hyponatremia. In multivariate analyses, an older age at admission (P = 0.006), male gender (P = 0.004), and increased CRP (P < 0.0001) were independent risk factors. Sodium levels correlated negatively with WBC (P = 0.037), CRP (P < 0.0001), and number of hospital days (P = 0.020). The AUC values of age (0.586, P < 0.0001), CRP (0.599, P < 0.0001), and blood urea nitrogen (0.559, P < 0.0001) were all significant predictors of hyponatremia. This study is the first to show that the incidence of hyponatremia differs according to infecting microorganism and radiological findings.
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