Evidence map›Paper›PMID 30404917›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

David P Doupé, Owen J Marshall, Hannah Dayton, Andrea H Brand, Norbert Perrimon

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cell-death induced immune response and coagulopathy promote cachexia inbioRxiv : the preprint server for biology · 2025
    Article
  8. Drosophila Intestine as a Model to Study Tumors.Advances in experimental medicine and biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Tissue Homeostasis and Non-Homeostasis: From Cell Life Cycles to Organ States.Annual review of cell and developmental biology · 2022
    Review
  16. Review
  17. Profiling Protein-DNA Interactions Cell-Type-Specifically with Targeted DamID.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  18. Epithelial Cell Polarity DuringFrontiers in cell and developmental biology · 2022
    Review
  19. Epithelial Stem Cells: Making, Shaping and Breaking the Niche.Advances in experimental medicine and biology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

David P DoupéDepartment of Genetics, Harvard Medical School, Boston, MA 02115; david.p.doupe@durham.ac.uk perrimon@receptor.med.harvard.edu.
Owen J MarshallThe Gurdon Institute, University of Cambridge, CB2 1QN Cambridge, United Kingdom.
Hannah DaytonDepartment of Genetics, Harvard Medical School, Boston, MA 02115.
Andrea H BrandThe Gurdon Institute, University of Cambridge, CB2 1QN Cambridge, United Kingdom.
Norbert PerrimonDepartment of Genetics, Harvard Medical School, Boston, MA 02115; david.p.doupe@durham.ac.uk perrimon@receptor.med.harvard.edu.
Harvard University · USWellcome/Cancer Research UK Gurdon Institute · GB

Funding

Tissue and Pathology ResourcesP50CA127003 · NCI · DANA-FARBER CANCER INST · PI EL-BARDEESY, NABEEL, SELLERS, WILLIAM R · 2007 to 2023
$33.2M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Biotechnology and Biological Sciences Research Council BB/L00786X/1Cancer Research UK C6946/A14492NCI NIH HHS P50 CA127003NIGMS NIH HHS R01 GM084947Wellcome TrustWellcome Trust 092096Wellcome Trust 092545Wellcome Trust 103792
6 · The paper itself

Abstract

Epithelial homeostasis requires the precise balance of epithelial stem/progenitor proliferation and differentiation. While many signaling pathways that regulate epithelial stem cells have been identified, it is probable that other regulators remain unidentified. Here, we use gene-expression profiling by targeted DamID to identify the stem/progenitor-specific transcription and signaling factors in the

Indexed as

Stem Cell NicheAnimalsDrosophilaDrosophila ProteinsHomeostasisIntestinesSignal TransductionStem CellsDrosophila Proteinsepithelial homeostasisinsulinmicroenvironmentnichestem cells

Identifiers

PMID30404917
PMCPMC6275525
OpenAlexW2899967253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.