Evidence map›Paper›PMID 30404653›Full record

ArticleActa neuropathologica communications2018

Satellite cells maintain regenerative capacity but fail to repair disease-associated muscle damage in mice with Pompe disease.

Gerben J Schaaf, Tom J M van Gestel, Stijn L M In 't Groen, Bart de Jong, Björn Boomaars, Antonietta Tarallo, Monica Cardone, Giancarlo Parenti, Ans T van der Ploeg, W W M Pim Pijnappel

Open access · goldAbstract read
In one paragraph

Article in Acta neuropathologica communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Skeletal Muscle Regeneration in Cardiotoxin-Induced Muscle Injury Models.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Lysosomes at the Crossroads of Cell Metabolism, Cell Cycle, and Stemness.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Article
  12. AnSTAR protocols · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Rescue of Advanced Pompe Disease in Mice with Hepatic Expression of Secretable Acid α-Glucosidase.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Gerben J SchaafDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Tom J M van GestelDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Stijn L M In 't GroenDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Bart de JongDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Björn BoomaarsDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Antonietta TaralloDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Monica CardoneDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Giancarlo ParentiDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Ans T van der PloegDepartment of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
W W M Pim PijnappelDepartment of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. w.pijnappel@erasmusmc.nl.ORCID 0000-0002-7042-2482
Erasmus MC · NLFederico II University Hospital · ITSt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pompe disease is a metabolic myopathy that is caused by glycogen accumulation as a result of deficiency of the lysosomal enzyme acid alpha glucosidase (GAA). Previously, we showed that adult muscle stem cells termed satellite cells are present at normal levels in muscle from patients with Pompe disease, but that these are insufficiently activated to repair the severe muscle pathology. Here we characterized the muscle regenerative response during disease progression in a mouse model of Pompe disease and investigated the intrinsic capacity of Gaa

Indexed as

Age Factorsalpha-GlucosidasesAnimalsBarium CompoundsCardiotoxinsChloridesDisease Models, AnimalFemaleGlycogenGlycogen Storage Disease Type IIKi-67 AntigenLamininLysosomal-Associated Membrane Protein 1MaleMiceMice, Inbred C57BLalpha-Glucosidasesbarium chlorideBarium CompoundsCardiotoxinsChloridesGlycogenKi-67 AntigenLamininLysosomal-Associated Membrane Protein 1Pax7 protein, mousePAX7 Transcription FactorGlycogenosis type IILysosomal storage diseaseMuscle regenerationPompe diseaseSatellite cells

Identifiers

PMID30404653
PMCPMC6220463
OpenAlexW2899714501

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.