Evidence map›Paper›PMID 30404643›Full record

ArticleBMC veterinary research2018

Isolation and characterization of GFAP-positive porcine neural stem/progenitor cells derived from a GFAP-CreER

Eunhye Kim, Seon-Ung Hwang, Junchul David Yoon, Hyunggee Kim, Gabsang Lee, Sang-Hwan Hyun

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. TH/TRs-COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eunhye KimLaboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Republic of Korea.
Seon-Ung HwangLaboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Republic of Korea.
Junchul David YoonLaboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Republic of Korea.
Hyunggee KimDepartment of Biotechnology, School of Life Sciences and Biotechnology, Korea University, 02841, Seoul, Republic of Korea.
Gabsang LeeInstitute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sang-Hwan HyunLaboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, 28644, Republic of Korea. shhyun@cbu.ac.kr.ORCID http://orcid.org/0000-0001-6011-2555
Chungbuk National University · KRJohns Hopkins University · USKorea University · KR

Funding

Business for Cooperative R&D between Industry, Academy, and Research Institute 2017020681010101Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET) 115103-02National Research Foundation of Korea NRF-2016R1D1A1B03933191, NRF-2017R1A2B4002546, 2017K1A4A3014959
6 · The paper itself

Abstract

backgroundThe porcine brain is gyrencephalic with similar gray and white matter composition and size more comparable to the human rather than the rodent brain; however, there is lack of information about neural progenitor cells derived from this model.

resultsHere, we isolated GFAP-positive porcine neural stem cells (NSCs) from the brain explant of a transgenic piglet, with expression of CreER

conclusionsCollectively, these results indicate that GFAP promoter-driven porcine CreER

Indexed as

AnimalsAnimals, Genetically ModifiedAnimals, NewbornAstrocytesCell DifferentiationGlial Fibrillary Acidic ProteinNeural Stem CellsSwineGlial Fibrillary Acidic ProteinNeural stem cellsNotch signalingPigReactive astrocytes

Identifiers

PMID30404643
PMCPMC6222979
OpenAlexW2899576372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.