ArticleBMC veterinary research2018
Hormonal and metabolic indicators before and after farrowing in sows affected with postpartum dysgalactia syndrome.
Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 56 citations in OpenAlex.
- Effect ofTranslational animal science · 2026Article
- Variations in Diacron-Reactive Oxygen Metabolites and Biological Antioxidant Potential Across Reproductive Phases and Parities in Sows Reared Under Different Production Systems.Animals : an open access journal from MDPI · 2025Article
- The Role of Nutrition Across Production Stages to Improve Sow Longevity.Animals : an open access journal from MDPI · 2025Review
- Elevated levels of C-reactive protein and pig major acute phase protein in lame gestating sows.Frontiers in veterinary science · 2025Article
- Failure in the mother-young communication in domestic mammals: endocrine and behavioral aspects.Frontiers in veterinary science · 2025Review
- Article
- Diagnostic utility of acute phase proteins and their ability to guide antibiotic usage in pigs, horses, and cattle: a mapping review.Acta veterinaria Scandinavica · 2024Review
- Effects ofAntioxidants (Basel, Switzerland) · 2024Article
- Impacts of Maternal Nutrition on Sow Performance and Potential Positive Effects on Piglet Performance.Animals : an open access journal from MDPI · 2024Review
- Evaluation of circulating immune cells, analytes, and inflammatory markers in sows affected with postpartum dysgalactia syndrome.Journal of animal science · 2024Article
- Digital documentation of treatment data and their relation to breed and performance parameters of sows.Archives animal breeding · 2024Article
- Effect of 1,25-dihydroxyvitamin D3-glycosides on postpartum health, uterine involution and litter performance of sows in a free farrowing system.Porcine health management · 2023Article
- Impact of body condition on sow and litter performance, postpartum physiological, hematological, and biochemical parameters in Landlly crossbred pigs.Tropical animal health and production · 2023Article
- Lactation in swine: review article.Animal frontiers : the review magazine of animal agriculture · 2023Review
- Changes in the Saliva Proteome of Pigs with Diarrhoea Caused byProteomes · 2023Article
- Serum Concentrations of Immunoglobulins and Cortisol Around Parturition in Clinically Healthy Sows and Sows with Postpartum Dysgalactia Syndrome (PDS).Journal of veterinary research · 2022Article
- Postpartum dysgalactia syndrome in sows: effects on behavior of sows and piglets.Porcine health management · 2022Article
- Basics for the potential use of saliva to evaluate stress, inflammation, immune system, and redox homeostasis in pigs.BMC veterinary research · 2022Review
- Characteristics of thermal images of the mammary gland and of performance in sows differing in health status and parity.Frontiers in veterinary science · 2022Article
- Micelle silymarin supplementation to sows' diet from day 109 of gestation to entire lactation period enhances reproductive performance and affects serum hormones and metabolites.Journal of animal science · 2021Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundPostpartum dysgalactia syndrome (PDS) in sows is difficult to diagnose and the pathogenesis is obscure. Hormonal changes related to the disease are often difficult to distinguish from those found in the normal transition period from gestation to lactation. The study aimed to investigate metabolic and hormonal changes related to PDS with the goal of identifying potential biomarkers in sows suffering from PDS (PDS+). Selected biomarkers were examined by comparing 38 PDS+ sows with 38 PDS negative (PDS-) sows. The sows were sampled every 24 h from 60 h ante partum (a.p.) to 36 h post partum (p.p.).
resultsCompared to the baseline (60 to 36 h a.p.), cortisol in serum and saliva and fasting blood glucose concentrations increased in PDS+ as well as PDS- sows. C-peptide decreased relative to the baseline in PDS+ sows, and prolactin and 8-epi prostaglandin F2 alpha (8-epi-PGF2α) decreased in PDS- sows. Concentrations of cortisol in serum and saliva, salivary chromogranin A (CgA), fasting blood glucose, C-peptide, and 8-epi-PGF2α differed significantly between PDS+ and PDS- sows, with levels of cortisol in serum and saliva, salivary CgA, and 8-epi-PGF2α in serum being different in the two groups already before parturition. Concentrations of salivary CgA were significantly lower in PDS- sows than in PDS+ sows during the entire study period.
conclusionsThe results suggest that salivary CgA, cortisol and serum 8-epi-PGF2α may potentially serve as early diagnostic indicators for PDS. The consistently higher salivary CgA concentration in PDS+ sows compared to PDS- sows may indicate that homeostatic disturbances are present between 36 to 60 h before parturition in sows developing PDS. The higher serum and saliva cortisol concentration in PDS+ sows compared to PDS- sows could reflect an early sign of inflammation or stress. The significantly lower C-peptide in PDS+ sows compared to PDS- sows may reflect a lower food intake. Our results contribute to the understanding of the pathogenesis of PDS, and the homeostatic disturbances detected before parturition warrants further investigation. The diagnostic potential of the markers identified in this study should be investigated further in a larger population of sows.
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