Evidence map›Paper›PMID 30404347›Full record

ArticleMicromachines2016

A Simple Method for Fabrication of Microstructures Using a PDMS Stamp.

Hun Lee, Domin Koh, Linfeng Xu, Sindhu Row, Stelios T Andreadis, Kwang W Oh

Abstract read
In one paragraph

Article in Micromachines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A SIMPLE ASPECT RATIO DEPENDENT METHOD OF PATTERNING MICROWELLS FOR SELECTIVE CELL ATTACHMENT.Proceedings of the ... Design of Medical Devices Conference. Design of Medical Devices Conference · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hun LeeSensors and MicroActuators Learning Laboratory (SMALL), Department of Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. hlee24@buffalo.edu.
Domin KohSensors and MicroActuators Learning Laboratory (SMALL), Department of Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. dominkoh@buffalo.edu.ORCID 0000-0002-6515-5543
Linfeng XuSensors and MicroActuators Learning Laboratory (SMALL), Department of Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. linfengx@buffalo.edu.ORCID 0000-0002-6386-1815
Sindhu RowDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. sindhuro@buffalo.edu.
Stelios T AndreadisDepartment of Chemical and Biological Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. sandread@buffalo.edu.
Kwang W OhSensors and MicroActuators Learning Laboratory (SMALL), Department of Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY 14260, USA. kwangoh@buffalo.edu.ORCID 0000-0003-0078-6683

Funding

National Science Foundation CBET-1337860National Science Foundation CBET-1403086
6 · The paper itself

Abstract

We report a simple method to fabricate PDMS (polydimethylsiloxane) microwell arrays on glass by using a PDMS stamp to study cell-to-cell adhesion. In the cell-to-cell study, a glass substrate is required since glass has better cell attachment. The microwell arrays are replicated from an SU-8 master mold, and then are transferred to a glass substrate by lifting the PDMS stamp, followed by oxygen plasma bonding of the PDMS stamp on the glass substrate. For the cell-to-cell adhesion, four different types of PDMS arrays (e.g., rectangle, bowtie, wide-rhombus, and rhombus) were designed to vary the cell-to-cell contact length. The transfer success rates of the microwell arrays were measured as a function of both the contact area of the PDMS and the glass substrate and the different ratios between the base polymers and the curing agent. This method of generating the microwell arrays will enable a simple and robust construction of PDMS-based devices for various biological applications.

Indexed as

cell-to-cell studyPDMS microwellPDMS microwell transferPDMS stamp

Identifiers

PMID30404347
PMCPMC6190059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.