ArticleMicromachines2016
High-Resolution Microfluidic Paper-Based Analytical Devices for Sub-Microliter Sample Analysis.
Article in Micromachines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Fabrication of Paper Microfluidic Chips via Wax Soft Lithography.Micromachines · 2026Article
- [Research progress on paper-based microfluidic chips in pathogen detection].Se pu = Chinese journal of chromatography · 2025Review
- Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module.Biosensors · 2023Review
- A Parametric Study on a Paper-Based Bi-Material Cantilever Valve.Micromachines · 2022Article
- Microfluidic Paper-Based Blood Plasma Separation Device as a Potential Tool for Timely Detection of Protein Biomarkers.Micromachines · 2022Article
- An Origami Paper-Based Analytical Device for Rapid and Sensitive Analysis of Acrylamide in Foods.Micromachines · 2021Article
- Integrated Microfluidic-Based Platforms for On-Site Detection and Quantification of Infectious Pathogens: Towards On-Site Medical Translation of SARS-CoV-2 Diagnostic Platforms.Micromachines · 2021Review
- Increasing the packing density of assays in paper-based microfluidic devices.Biomicrofluidics · 2021Review
- Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives.Microfluidics and nanofluidics · 2021Review
- Citizen-led sampling to monitor phosphate levels in freshwater environments using a simple paper microfluidic device.PloS one · 2021Article
- Three-Dimensional Paper-Based Microfluidic Analysis Device for Simultaneous Detection of Multiple Biomarkers with a Smartphone.Biosensors · 2020Article
- Fabrication of paper microfluidic devices using a toner laser printer.RSC advances · 2020Article
- Pushing the Limits of Spatial Assay Resolution for Paper-Based Microfluidics Using Low-Cost and High-Throughput Pen Plotter Approach.Micromachines · 2020Article
- Counting-based microfluidic paper-based devices capable of analyzing submicroliter sample volumes.Biomicrofluidics · 2020Article
- Programmable Paper-Based Microfluidic Devices for Biomarker Detections.Micromachines · 2019Review
- Fabrication of Miniaturized Paper-Based Microfluidic Devices (MicroPADs).Scientific reports · 2019Article
- Paper-Based Antibody Detection Devices Using Bioluminescent BRET-Switching Sensor Proteins.Angewandte Chemie (International ed. in English) · 2018Article
- "Dip-and-read" paper-based analytical devices using distance-based detection with color screening.Lab on a chip · 2018Article
- Features in Microfluidic Paper-Based Devices Made by Laser Cutting: How Small Can They Be?Micromachines · 2018Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work demonstrates the fabrication of microfluidic paper-based analytical devices (µPADs) suitable for the analysis of sub-microliter sample volumes. The wax-printing approach widely used for the patterning of paper substrates has been adapted to obtain high-resolution microfluidic structures patterned in filter paper. This has been achieved by replacing the hot plate heating method conventionally used to melt printed wax features into paper by simple hot lamination. This patterning technique, in combination with the consideration of device geometry and the influence of cellulose fiber direction in filter paper, led to a model µPAD design with four microfluidic channels that can be filled with as low as 0.5 µL of liquid. Finally, the application to a colorimetric model assay targeting total protein concentrations is shown. Calibration curves for human serum albumin (HSA) were recorded from sub-microliter samples (0.8 µL), with tolerance against ±0.1 µL variations in the applied liquid volume.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.