Evidence map›Paper›PMID 30404196›Full record

ArticleInternational journal of molecular sciences2018

Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties.

Phurpa Wangchuk, Simon H Apte, Michael J Smout, Penny L Groves, Alex Loukas, Denise L Doolan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. A Review of Approaches Developed for Spiroether Synthesis.Topics in current chemistry (Cham) · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. A comprehensive review ofFrontiers in pharmacology · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Plant Natural Products for Human Health.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Phurpa WangchukCentre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4878, Australia. phurpa.wangchuk@jcu.edu.au.
Simon H ApteQIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. Simon.Apte@health.qld.gov.au.
Michael J SmoutCentre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4878, Australia. michael.smout@jcu.edu.au.ORCID 0000-0001-6937-0112
Penny L GrovesQIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. Penny.Groves@qimrberghofer.edu.au.
Alex LoukasCentre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4878, Australia. alex.loukas@jcu.edu.au.
Denise L DoolanCentre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4878, Australia. denise.doolan@jcu.edu.au.
Australian Institute of Tropical Health and Medicine · AUQIMR Berghofer Medical Research Institute · AU

Funding

National Health and Medical Research Council 1117504National Health and Medical Research Council 1137285National Health and Medical Research Council APP1091011
6 · The paper itself

Abstract

Plant-derived compounds that modulate the immune responses are emerging as frontline treatment agents for cancer, infectious diseases and autoimmunity. Herein we have isolated 40 phytochemicals from five Bhutanese

Indexed as

Cell Line, TumorChondrocytesDendritic CellsGene Expression RegulationHumansImmunologic FactorsMedicine, TraditionalMolecular StructurePhytochemicalsPlant ExtractsPlants, MedicinalImmunologic FactorsPhytochemicalsPlant Extractsadjuvantbergaptencytoxicitydendritic cellsimmune modulationimmunomodulatormedicinal plantsphytochemicalsscoulerine

Identifiers

PMID30404196
PMCPMC6274922
OpenAlexW2899930031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.