Trial reportPloS one2018
Effects of a preconception lifestyle intervention in obese infertile women on diet and physical activity; A secondary analysis of a randomized controlled trial.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Association between physical activity and infertility: a comprehensive systematic review and meta-analysis.Journal of translational medicine · 2022Pooled it
- Preconception lifestyle advice for people with infertility.The Cochrane database of systematic reviews · 2021Pooled it
- Effectiveness of a complex, pre-conception intervention to reduce the risk of diabetes by reducing adiposity in young adults in Malaysia: The Jom Mama project - A randomised controlled trial.Journal of global health · 2022Trial
- Preconception lifestyle intervention in women with obesity and echocardiographic indices of cardiovascular health in their children.International journal of obesity (2005) · 2022Trial
- A lifestyle intervention randomized controlled trial in obese women with infertility improved body composition among those who experienced childhood adversity.Stress and health : journal of the International Society for the Investigation of Stress · 2021Trial
- Preconception Lifestyle and Cardiovascular Health in the Offspring of Overweight and Obese Women.Nutrients · 2019Trial
- Preconception lifestyle intervention reduces long term energy intake in women with obesity and infertility: a randomised controlled trial.The international journal of behavioral nutrition and physical activity · 2019Trial
- Cardiometabolic Health in Relation to Lifestyle and Body Weight Changes 3⁻8 Years Earlier.Nutrients · 2018Trial
- Lifestyle Modifications Prior to Pregnancy and Their Impact on Maternal and Perinatal Outcomes: A Review.Journal of clinical medicine · 2025Review
- Association between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women.Lipids in health and disease · 2024Article
- Article
- The importance of nutrition in pregnancy and lactation: lifelong consequences.American journal of obstetrics and gynecology · 2022Review
- Article
- Article
- Article
- Lifestyle intervention prior to IVF does not improve embryo utilization rate and cumulative live birth rate in women with obesity: a nested cohort study.Human reproduction open · 2021Article
- Pre-Conception Interventions for Subfertile Couples Undergoing Assisted Reproductive Technology Treatment: Modeling Analysis.JMIR mHealth and uHealth · 2020Article
- Creating Healthy Change in the Preconception Period for Women with Overweight or Obesity: A Qualitative Study Using the Information-Motivation-Behavioural Skills Model.Journal of clinical medicine · 2020Article
- The Case for Bringing Birthweight to Adult Cardiovascular Medicine.The American journal of cardiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLifestyle changes are notoriously difficult. Since women who intend to become pregnant are more susceptible to lifestyle advice, interventions during this time window might be more effective than interventions during any other period in life. We here report the effects of the first large preconception lifestyle intervention RCT on diet and physical activity in obese infertile women.
methodsIn total, 577 women were randomized between a six-month lifestyle intervention program (intervention group; N = 290) or prompt infertility treatment (control group; N = 287). Self-reported dietary behaviors and physical activity were assessed at baseline, three, six and twelve months after randomization. Mixed models were used to analyze differences between groups.
resultsCompared to the control group, the intervention group reduced their intake of sugary drinks at three months (-0.5 glasses/day [95% C.I. = -0.9;-0.2]), of savory snacks at three (-2.4 handful/week [-3.4;-1.4]) and at six months (-1.4 handful/week [-2.6;-0.2]), and of sweet snacks at three (-2.2 portion/week [-3.3;-1.0]) and twelve months after randomization (-1.9 portion/week [-3.5;-0.4]). Also, the intervention group was more moderate to vigorous physically active at three months after randomization compared to the control group (169.0 minutes/week [6.0; 332.1]).
conclusionOur study showed that obese infertile women who followed a six-month preconception lifestyle intervention program decreased their intake of high caloric snacks and beverages, and increased their physical activity. These changes in lifestyle may not only improve women's health but their offspring's health too.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.