ArticleCancer2018
Pregnancy after cancer: Does timing of conception affect infant health?
Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Cancer and fertility management: FIGO best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Guideline
- Pregnancy after cancer: FIGO Best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Guideline
- Reproductive outcomes of pregnancy after breast cancer: an updated systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Outcomes after assisted reproductive technology in women with cancer: a systematic review and meta-analysis.Human reproduction (Oxford, England) · 2023Pooled it
- Breastfeeding is Possible: A Systematic Review on the Feasibility and Challenges of Breastfeeding Among Breast Cancer Survivors of Reproductive Age.Annals of surgical oncology · 2021Pooled it
- Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer.The New England journal of medicine · 2023Trial
- Updated results of the POSITIVE (Pregnancy Outcome and Safety of Interrupting Therapy for Women with Endocrine Responsive Breast Cancer) trial.Annals of oncology : official journal of the European Society for Medical Oncology · 2026Article
- Reproductive Challenges in Mutated BRCA Gene Carriers: A Narrative Review.Current issues in molecular biology · 2026Review
- Leukemia during pregnancy and survivorship: gestational age-stratified multidisciplinary management framework.Clinical and experimental medicine · 2026Review
- Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment.Annals of medicine · 2025Article
- Gonadotoxicity of immunotherapy and targeted agents in patients with cancer and impact on subsequent pregnancies.Human reproduction (Oxford, England) · 2025Review
- The prevalence of parental cancer history and in vitro fertilization utilization.Journal of the National Cancer Institute · 2025Article
- Article
- Pregnancy Complicated by Rapidly Progressing Vulvar Melanoma: A Case Study.The American journal of case reports · 2025Article
- Pregnancy after breast cancer: latest evidence and practical considerations.Therapeutic advances in medical oncology · 2025Review
- Influence of cancer in pregnancy on obstetric and neonatal outcomes: an observational retrospective cohort study.Journal of gynecologic oncology · 2024Observational
- A Scoping Review of Preterm Birth Risk Factors.American journal of perinatology · 2024Article
- Article
- Obstetric and perinatal outcomes in women with previous breast cancer: a nationwide study of singleton births 1973-2017.Human reproduction open · 2024Article
- Challenges and Opportunities of Epidemiological Studies to Reduce the Burden of Cancers in Young Adults.Current epidemiology reports · 2023Article
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7 authors.
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Abstract
backgroundThe objective of this retrospective cohort study was to determine whether women who conceive soon after treatment for cancer have higher risks of adverse pregnancy outcomes.
methodsVital records data were linked to cancer registry diagnosis and treatment information in 3 US states. Women who conceived their first pregnancy after diagnosis between ages 20 and 45 years with any invasive cancer or ductal carcinoma in situ were eligible. Log-binomial models were used to compare risks in cancer survivors who conceived in each interval to the risks in matched comparison births to women without cancer.
resultsWomen who conceived ≤1 year after starting chemotherapy for any cancer had higher risks of preterm birth than comparison women (chemotherapy alone: relative risk [RR], 1.9; 95% confidence interval [CI], 1.3-2.7; chemotherapy with radiation: RR, 2.4; 95% CI, 1.6-3.6); women who conceived ≥1 year after starting chemotherapy without radiation or ≥2 years after chemotherapy with radiation did not. In analyses imputing the treatment end date for breast cancer survivors, those who conceived ≥1 year after finishing chemotherapy with or without radiation had no higher risks than women without cancer. The risk of preterm birth in cervical cancer survivors largely persisted but was somewhat lower in pregnancies conceived after the first year (for pregnancies conceived ≤1 year after diagnosis: RR, 3.5; 95% CI, 2.2-5.4; for pregnancies conceived >1 year after diagnosis: RR, 2.4; 95% CI, 1.6-3.5).
conclusionsIn women who received chemotherapy, the higher risk of preterm birth was limited to those survivors who had short intervals between treatment and conception.Cancer 2018;124:000-000.
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