Evidence map›Paper›PMID 30403291›Full record

ArticleFEBS letters2018

Effects of stably incorporated iron on protein phosphatase-1 structure and activity.

Francesca Salvi, Malgorzata Trebacz, Thomas Kokot, Bernhard Hoermann, Pablo Rios, Orsolya Barabas, Maja Köhn

Open access · greenAbstract read
In one paragraph

Article in FEBS letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Structural insights into the dual CaNature communications · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  13. Article
  14. SDS22 selectively recognizes and traps metal-deficient inactive PP1.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francesca SalviGenome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Malgorzata TrebaczFaculty of Biology and Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Germany.
Thomas KokotFaculty of Biology and Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Germany.
Bernhard HoermannFaculty of Biology and Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Germany.
Pablo RiosFaculty of Biology and Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Germany.
Orsolya BarabasStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Maja KöhnGenome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0001-8142-3504
University of Freiburg · DEEuropean Molecular Biology Laboratory · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein phosphatase-1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes to counteract multiple kinases in signaling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains iron naturally. Iron has been suggested to have an influence on PP1 activity through Fe

Indexed as

Crystallography, X-RayEscherichia coliHumansIronManganeseModels, MolecularOxidation-ReductionProtein DomainsProtein Phosphatase 1Recombinant ProteinsSubstrate SpecificityIronManganeseProtein Phosphatase 1Recombinant Proteinsmetalloenzymephosphatase activityprotein phosphatase-1redox regulationX-ray crystallography

Identifiers

PMID30403291
PMCPMC6587554
OpenAlexW2899887642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.