Evidence map›Paper›PMID 30403019›Full record

ArticleKorean circulation journal2018

Left Ventricular Ejection Fraction Predicts Poststroke Cardiovascular Events and Mortality in Patients without Atrial Fibrillation and Coronary Heart Disease.

Jeong Yoon Lee, Jun Sang Sunwoo, Kyum Yil Kwon, Hakjae Roh, Moo Young Ahn, Min Ho Lee, Byoung Won Park, Min Su Hyon, Kyung Bok Lee

Open access · hybridAbstract read
In one paragraph

Article in Korean circulation journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Unravelling the role of electrocardiogram changes and ejection fraction in ischaemic stroke outcomes.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  2. Review
  3. Article
  4. Predicting adverse cardiovascular outcomes in post-coronary artery bypass grafting patients using novel ECG frequency analysis of the QRS complex.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jeong Yoon LeeDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4297-1791
Jun Sang SunwooDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8168-3127
Kyum Yil KwonDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5443-0952
Hakjae RohDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0979-4279
Moo Young AhnDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0329-5855
Min Ho LeeDepartment of Cardiology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0748-7766
Byoung Won ParkDepartment of Cardiology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6986-2803
Min Su HyonDepartment of Cardiology, Soonchunhyang University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9057-8700
Kyung Bok LeeDepartment of Neurology, Soonchunhyang University School of Medicine, Seoul, Korea. kblee@schmc.ac.kr.ORCID https://orcid.org/0000-0003-2663-7483
Soonchunhyang University · KR

Funding

CJ Healthcare Corp.Soonchunhyang University
6 · The paper itself

Abstract

BACKGROUND AND

objectivesIt is controversial that decreased left ventricular function could predict poststroke outcomes. The purpose of this study is to elucidate whether left ventricular ejection fraction (LVEF) can predict cardiovascular events and mortality in acute ischemic stroke (AIS) without atrial fibrillation (AF) and coronary heart disease (CHD).

methodsTransthoracic echocardiography was conducted consecutively in patients with AIS or transient ischemic attack at Soonchunhyang University Hospital between January 2008 and July 2016. The clinical data and echocardiographic LVEF of 1,465 patients were reviewed after excluding AF and CHD. Poststroke disability, major adverse cardiac events (MACE; nonfatal stroke, nonfatal myocardial infarction, and cardiovascular death) and all-cause mortality during 1 year after index stroke were prospectively captured. Cox proportional hazards regressions analysis were applied adjusting traditional risk factors and potential determinants.

resultsThe mean follow-up time was 259.9±148.8 days with a total of 29 non-fatal strokes, 3 myocardial infarctions, 33 cardiovascular deaths, and 53 all-cause mortality. The cumulative incidence of MACE and all-cause mortality were significantly higher in the lowest LVEF (<55) group compared with the others (p=0.022 and 0.009). In prediction models, LVEF (per 10%) had hazards ratios of 0.54 (95% confidence interval [CI], 0.36-0.80, p=0.002) for MACE and 0.61 (95% CI, 0.39-0.97, p=0.037) for all-cause mortality.

conclusionsLVEF could be an independent predictor of cardiovascular events and mortality after AIS in the absence of AF and CHD.

Indexed as

EchocardiographyLeft ventricular functionMortalityStroke

Identifiers

PMID30403019
PMCPMC6221865
OpenAlexW2888272442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.