Evidence map›Paper›PMID 30403006›Full record

Trial reportJournal of clinical hypertension (Greenwich, Conn.)2018

Comparison of automated clinical and research blood pressure measurements: Implications for clinical practice and trial design.

Olive Tang, Stephen P Juraschek, Lawrence J Appel, Lisa A Cooper, Jeanne Charleston, Romsai T Boonyasai, Kathryn A Carson, Hsin-Chieh Yeh, Edgar R Miller

Open access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Olive TangThe Johns Hopkins School of Medicine, Baltimore, Maryland.ORCID 0000-0002-1974-4857
Stephen P JuraschekBeth Israel Deaconess Medical Center, Boston, Massachusetts.
Lawrence J AppelThe Johns Hopkins School of Medicine, Baltimore, Maryland.
Lisa A CooperThe Johns Hopkins School of Medicine, Baltimore, Maryland.
Jeanne CharlestonThe Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Romsai T BoonyasaiThe Johns Hopkins School of Medicine, Baltimore, Maryland.ORCID 0000-0003-0650-9548
Kathryn A CarsonThe Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Hsin-Chieh YehThe Johns Hopkins School of Medicine, Baltimore, Maryland.
Edgar R MillerThe Johns Hopkins School of Medicine, Baltimore, Maryland.
Johns Hopkins University · USBeth Israel Deaconess Medical Center · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007309 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 1985 to 2019
$43.2M
Comparative Effectiveness of Health System vs. Multilevel Interventions to Reduce Hypertension DisparitiesUH3HL130688 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI COOPER, LISA A, MARSTELLER, JILL ANNE · 2016 to 2019
$11.2M
TRAINING COREP50HL105187 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GOLDEN, SHERITA HILL · 2010 to 2014
$9.8M
Vitamin D, Subclinical Cardiovascular Disease, and Orthostatic Hypotension in Older AdultsK23HL135273 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2017 to 2021
$1.1M
Racial disparities in diabetes- and prediabetes-associated outcomes in older adultsF30DK120160 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TANG, OLIVE · 2018 to 2020
$145k
NHLBI NIH HHS K23 HL135273NHLBI NIH HHS P50 HL105187NHLBI NIH HHS UH3 HL130688NIDDK NIH HHS F30 DK120160NIGMS NIH HHS T32 GM007309
6 · The paper itself

Abstract

Discrepancies between clinic and research blood pressure (BP) measurements lead to uncertainties in translating hypertension management guidelines into practice. We assessed the concordance between standardized automated clinic BP, from a primary care clinic, and research BP, from a randomized trial conducted at the same site. Mean single-visit clinic BP was higher by 4.4/3.8 mm Hg (P = 0.007/<0.001). Concordance in systolic BP (SBP) improved with closer proximity of measurements (difference = 2.5 mm Hg, P = 0.21 for visits within 7 days), but not averaging across multiple visits (difference =5.1(9.2) mm Hg; P < 0.001). This discrepancy was greater among female participants. Clinic-based difference in SBP between two visits was more variable than research-based change (SD = 19.6 vs 14.0; P = 0.002); a 2-arm trial using clinic measurements would need 95% more participants to achieve comparable power. Implementation of a bundled standardization intervention decreased discrepancies between clinic and research BP, compared to prior reports. However, clinic measurements remained higher and more variable, suggesting treatment to research-based targets may lead to overtreatment and using clinic BP approximately halves power in trials.

Indexed as

AgedBlack or African AmericanBlood PressureBlood Pressure DeterminationElectronic Health RecordsFemaleHumansHypertensionMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Reproducibility of ResultsRetrospective Studiesblood pressure measurementclinical trialselectronic health recordhypertensionstandardized blood pressure protocol

Identifiers

PMID30403006
PMCPMC6289771
OpenAlexW2899829317

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.