Evidence map›Paper›PMID 30402794›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Impact of age on elderly patients with oral cancer.

Akshat Malik, Aseem Mishra, Prashant Chopda, Hitesh Singhvi, Sudhir Nair, Deepa Nair, Sarbani Ghosh Laskar, Kumar Prabhash, Jai Prakash Agarwal, Pankaj Chaturvedi

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Recent Advances in Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2022
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Akshat MalikDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Aseem MishraDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Prashant ChopdaDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Hitesh SinghviDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Sudhir NairDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Deepa NairDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India.
Sarbani Ghosh LaskarDepartment of Radiation Oncology, Tata Memorial Centre, Mumbai, India.
Kumar PrabhashDepartment of Medical Oncology, Tata Memorial Centre, Mumbai, India.
Jai Prakash AgarwalDepartment of Radiation Oncology, Tata Memorial Centre, Mumbai, India.
Pankaj ChaturvediDepartment of Head and Neck Oncology, Tata Memorial Centre, Mumbai, India. chaturvedi.pankaj@gmail.com.ORCID http://orcid.org/0000-0003-1829-3537
Tata Memorial Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn this study we have tried to analyze the impact of age on various clinico-pathological parameters, treatment completion and subsequent survival in older patients. MATERIALS AND

methodsThis is a retrospective analysis of 140 elderly (> 65 years) patients of oral cancer operated between January 2012 and December 2013. The patients were divided into two groups based upon their age that ≤ 70 years and > 70 years.Association of distribution of various clinico-pathological factors between different groups was assessed by using Chi-square test. Survival analysis was done using Kaplan Meir analysis. Univariate and multivariate analysis were performed.

resultsThe two groups had similar distribution of various clinico-pathological factors. Disease free survival for the group ≤ 70 and > 70 years was 37.6 months and 36.4 months (p < 0.594). 13.5% and 7.8% patients > 70 years and ≤ 70 years were either advised or received sub-optimal adjuvant therapy (p < 0.002).

conclusionThere is no difference distribution of various clinico-pathological factors and survival in patients of oral cancer ≤ 70 and > 70 years of age. Age did not affect survival. Majority of patients could complete the adjuvant therapy advised. Still, significantly more number of patients > 70 years could not receive/complete appropriate adjuvant therapy. Thus treatment needs to be tailored keeping in mind the individual's performance status and the co-morbidities.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsAgedAged, 80 and overAge FactorsChi-Square DistributionCombined Modality TherapyFemaleHumansMaleMultivariate AnalysisPrognosisRetrospective StudiesSurvival AnalysisAdjuvant therapyAgeGeriatric patientsOral cancerSurvival

Identifiers

PMID30402794
OpenAlexW2899954876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.