Evidence map›Paper›PMID 30402705›Full record

Trial reportEuropean radiology2019

Patients' experience of screening CT colonography with reduced and full bowel preparation in a randomised trial.

Lapo Sali, Leonardo Ventura, Grazia Grazzini, Alessandra Borgheresi, Silvia Delsanto, Massimo Falchini, Beatrice Mallardi, Paola Mantellini, Stefano Milani, Stefano Pallanti and 2 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. [CT colonography : Technique and indications].Radiologie (Heidelberg, Germany) · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lapo SaliDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy. lapo.sali@unifi.it.ORCID http://orcid.org/0000-0002-3366-1660
Leonardo VenturaInstitute for Cancer Research, Prevention and Oncological Network (ISPRO), Via Cosimo il Vecchio 2, 50139, Florence, Italy.
Grazia GrazziniInstitute for Cancer Research, Prevention and Oncological Network (ISPRO), Via Cosimo il Vecchio 2, 50139, Florence, Italy.
Alessandra BorgheresiSchool of Radiology, Università Politecnica delle Marche, Piazza Roma 22, 60121, Ancona, Italy.
Silvia Delsantoim3D S.p.A, Via Livorno 60, 10153, Turin, Italy.
Massimo FalchiniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy.
Beatrice MallardiInstitute for Cancer Research, Prevention and Oncological Network (ISPRO), Via Cosimo il Vecchio 2, 50139, Florence, Italy.
Paola MantelliniInstitute for Cancer Research, Prevention and Oncological Network (ISPRO), Via Cosimo il Vecchio 2, 50139, Florence, Italy.
Stefano MilaniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy.
Stefano PallantiDepartment of Health Sciences, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Marco ZappaInstitute for Cancer Research, Prevention and Oncological Network (ISPRO), Via Cosimo il Vecchio 2, 50139, Florence, Italy.
Mario MascalchiDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Viale Morgagni 50, 50134, Florence, Italy.
University of Florence · ITInstitute for the Dynamics of Environmental Processes · ITMarche Polytechnic University · IT

Funding

Ente Cassa di Risparmio di Firenze (IT) 2012.0742A2202.3931Regione Toscana (IT) POR CREO FESR 1.1c
6 · The paper itself

Abstract

objectivesTo assess patients' experience of bowel preparation and procedure for screening CT colonography with reduced (r-CTC) and full cathartic preparation (f-CTC) that showed similar detection rate for advanced neoplasia in a randomised trial.

methodsSix hundred seventy-four subjects undergoing r-CTC and 612 undergoing f-CTC in the SAVE trial were asked to complete two pre-examination questionnaires-(1) Life Orientation Test - Revised (LOT-R) assessing optimism and (2) bowel preparation questionnaire-and a post-examination questionnaire evaluating overall experience of CTC screening test. Items were analysed with chi-square and t test separately and pooled.

resultsLOT-R was completed by 529 (78%) of r-CTC and by 462 (75%) of f-CTC participants and bowel preparation questionnaire by 531 (79%) subjects in the r-CTC group and by 465 (76%) in the f-CTC group. Post-examination questionnaire was completed by 525 (78%) subjects in the r-CTC group and by 453 (74%) in the f-CTC group. LOT-R average score was not different between r-CTC (14.27 ± 3.66) and f-CTC (14.54 ± 3.35) (p = 0.22). In bowel preparation questionnaire, 88% of r-CTC subjects reported no preparation-related symptoms as compared to 70% of f-CTC subjects (p < 0.001). No interference of bowel preparation with daily activities was reported in 80% of subjects in the r-CTC group as compared to 53% of subjects in the f-CTC group (p < 0.001). In post-examination questionnaire, average scores for discomfort of the procedure were not significantly different between r-CTC (3.53 ± 0.04) and f-CTC (3.59 ± 0.04) groups (p = 0.84).

conclusionsReduced bowel preparation is better tolerated than full preparation for screening CT colonography. KEY POINTS: • Reduced bowel preparation is better tolerated than full preparation for screening CT colonography. • Procedure-related discomfort of screening CT colonography is not influenced by bowel preparation. • Males tolerate bowel preparation and CT colonography screening procedure better than females.

Indexed as

Patient SatisfactionCatharticsColonography, Computed TomographicColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMass ScreeningMiddle AgedReproducibility of ResultsSurveys and QuestionnairesCatharticsCT colonographyQuestionnaireVirtual colonoscopy

Identifiers

PMID30402705
OpenAlexW2899538218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.