ArticleAllergologie select2017
The German Infant Nutritional Intervention Study (GINI) for the preventive effect of hydrolyzed infant formulas in infants at high risk for allergic diseases. Design and selected results.
Article in Allergologie select, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Infant formulas containing hydrolysed protein for prevention of allergic disease.The Cochrane database of systematic reviews · 2018Pooled it
- WITHDRAWN: Infant formulas containing hydrolysed protein for prevention of allergic disease and food allergy.The Cochrane database of systematic reviews · 2017Pooled it
- Infant formulas containing hydrolysed protein for prevention of allergic disease and food allergy.The Cochrane database of systematic reviews · 2017Pooled it
- Trial
- Extensively hydrolyzed versus intact milk protein formula and risk of necrotizing enterocolitis: a meta-analysis.Frontiers in pediatrics · 2026Review
- Early life acute infections and risk for cow's milk protein allergy or atopic dermatitis at 6 months of age in high risk for allergy infants.Frontiers in pediatrics · 2024Article
- Ruminococcus gnavus: friend or foe for human health.FEMS microbiology reviews · 2023Review
- Cost-effectiveness of infant hypoallergenic formulas to manage cow's milk protein allergy in France.Journal of market access & health policy · 2023Article
- Camel Milk Cannot Prevent the Development of Cow's Milk Allergy-A Study in Brown Norway Rats.Molecular nutrition & food research · 2023Article
- Alternatives to Cow's Milk-Based Infant Formulas in the Prevention and Management of Cow's Milk Allergy.Foods (Basel, Switzerland) · 2022Review
- Managing Cow's Milk Protein Allergy in Indonesia: A Cost-effectiveness Analysis of Hypoallergenic Milk Formulas from the Private Payers' Perspective.Journal of health economics and outcomes research · 2022Article
- Pediatric Obesity-Related Asthma: The Role of Nutrition and Nutrients in Prevention and Treatment.Nutrients · 2021Review
- Cost-effectiveness Analysis of Hypoallergenic Milk Formulas for the Management of Cow's Milk Protein Allergy in the United Kingdom.Journal of health economics and outcomes research · 2021Article
- Administration of Extensive Hydrolysates From Caseins andFrontiers in immunology · 2020Article
- Tolerogenic Effect Elicited by Protein Fraction Derived From Different Formulas for Dietary Treatment of Cow's Milk Allergy in Human Cells.Frontiers in immunology · 2020Article
- Nutritional Factors in the Prevention of Atopic Dermatitis in Children.Frontiers in pediatrics · 2020Review
- Dietary Interventions and Nutritional Factors in the Prevention of Pediatric Asthma.Frontiers in pediatrics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the complex interaction between certain environmental factors and genetic disposition, the early allergen exposure plays a major role in the development of allergic diseases. In aiming to reduce the allergen burden for the infant at risk during early infancy, cow's milk protein hydrolysate infant formulas (hypoallergenic infant formulas) are appropriate alternatives to breastfeeding for primary allergy prevention. The
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.