ArticleImmune network2018
Validation Study of an Operational Tolerance Signature in Korean Kidney Transplant Recipients.
Article in Immune network, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Urinary mRNA biomarkers for the noninvasive diagnosis of calcineurin inhibitor toxicity in kidney transplant recipients with graft dysfunction: a retrospective study.Clinical transplantation and research · 2025Article
- Article
- Phenotype and molecular signature of CD8+ T cell subsets in T cell- mediated rejections after kidney transplantation.PloS one · 2020Article
- Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy.Immune network · 2019Article
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Authors and funding
14 authors.
Funding
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Abstract
Operational tolerance (OT), defined as maintaining stable graft function without immunosuppression after transplant surgery, is an ideal goal for kidney transplant recipients (KTRs). Recent investigations have demonstrated the distinctive features of B cells, T cells, and dendritic cell-related gene signatures and the distributions of circulating lymphocytes in these patients; nonetheless, substantial heterogeneities exist across studies. This study was conducted to determine whether previously reported candidate gene biomarkers and the profiles of lymphocyte subsets of OT could be applied in Korean KTRs. Peripheral blood samples were collected from 153 patients, including 7 operationally tolerant patients. Quantitative real-time PCR and flow cytometry were performed to evaluate gene expression and lymphocyte subsets, respectively. Patients with OT showed significantly higher levels of B cell-related gene signatures (
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