Evidence map›Paper›PMID 30402273›Full record

ArticleRMD open2018

Relapsing polychondritis: state of the art on clinical practice guidelines.

Simona Rednic, Laura Damian, Rosaria Talarico, Carlo Alberto Scirè, Alexander Tobias, Nathalie Costedoat-Chalumeau, David Launay, Alexis Mathian, Lisa Mattews, Cristina Ponte and 8 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 6 countries.

Simona RednicDepartment of Rheumatology, Emergency County Teaching Hospital, Cluj-Napoca, Romania.
Laura DamianDepartment of Rheumatology, Emergency County Teaching Hospital, Cluj-Napoca, Romania.
Rosaria TalaricoRheumatology Unit, AOU Pisana, Pisa, Italy.
Carlo Alberto ScirèDepartment of Medical Sciences, Section of Rheumatology, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-7451-0271
Alexander TobiasDepartment of Rheumatology and Clinical Immunology, Charité University Hospital Berlin, Berlin, Germany.ORCID 0000-0003-1193-0097
Nathalie Costedoat-ChalumeauAssistance Publique-Hôpitaux de Paris (AP-HP), Cochin Hospital, Internal Medicine Department, Referral Center for Rare Autoimmune and Systemic Diseases, Paris, France.
David LaunayDépartement de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Systémiques et Auto-Immunes Rares du Nord-Ouest (CERAINO), LIRIC, INSERM, Univ. Lille, CHU Lille, Lille, France.
Alexis MathianDepartment of Internal Medicine, Hospital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France.
Lisa MattewsRelapsing Polychondritis Awareness and Support, Worcester, UK.
Cristina PonteDepartment of Rheumatology, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon Academic Medical Centre, Lisbon, Portugal.
Paola ToniatiRheumatology and Clinical Immunology Unit, Civil Hospital, Brescia, Italy.
Stefano BombardieriUniversity of Pisa, Pisa, Italy.
Charissa FrankBindweefsel.be, Koersel, Belgium.
Matthias SchneiderDepartment of Rheumatology, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Vanessa SmithDepartment of Rheumatology, Ghent University Hospital, Ghent, Belgium.
Maurizio CutoloResearch Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS Polyclinic Hospital San Martino, University of Genoa, Genoa, Italy.
Marta MoscaRheumatology Unit, AOU Pisana, Pisa, Italy.
Laurent ArnaudService de rhumatologie, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares (RESO), INSERM-UMRS 1109, F-67000, Strasbourg, France.
Clinical Emergency Hospital Bucharest · ROInserm · FRUniversity of Pisa · ITCentro Hospitalar Lisboa Norte · PTCharité - Universitätsmedizin Berlin · DEDélégation Paris 5 · FRDüsseldorf University Hospital · DEGhent University Hospital · BEOspedale Policlinico San Martino · ITSorbonne Université · FRUniversity of Brescia · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the rarity of relapsing polychondritis (RP), many unmet needs remain in the management of RP. Here, we present a systematic review of clinical practice guidelines (CPGs) published for RP, as well as a list of the most striking unmet needs for this rare disease. We carried out a systematic search in PubMed and Embase based on controlled terms (medical subject headings and Emtree) and keywords of the disease and publication type (CPGs). The systematic literature review identified 20 citations, among which no CPGs could be identified. We identified 11 main areas with unmet needs in the field of RP: the diagnosis strategy for RP; the therapeutic management of RP; the management of pregnancy in RP; the management of the disease in specific age groups (for instance in paediatric-onset RP); the evaluation of adherence to treatment; the follow-up of patients with RP, including the frequency of screening for the potential complications and the optimal imaging tools for each involved region; perioperative and anaesthetic management (due to tracheal involvement); risk of neoplasms in RP, including haematological malignancies; the prevention and management of infections; tools for assessment of disease activity and damage; and patient-reported outcomes and quality of life indicators. Patients and physicians should work together within the frame of the ReCONNET network to derive valuable evidence for obtaining literature-informed CPGs.

Indexed as

clinical practice guidelineseuropean references networksReCONNETrelapsing polychondritisunmet needs

Identifiers

PMID30402273
PMCPMC6203097
OpenAlexW2897499144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.