Evidence map›Paper›PMID 30401957›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2019

Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.

Marina C G Harvie, Donald P McManus, Hong You, Vanessa A Rivera, Sujeevi K Nawaratna, Kelli P A MacDonald, Grant A Ramm, Geoffrey N Gobert

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Marina C G HarvieQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Donald P McManusQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Hong YouQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Vanessa A RiveraQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Sujeevi K NawaratnaQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Kelli P A MacDonaldQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Grant A RammQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Geoffrey N GobertQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. g.gobert@qub.ac.uk.ORCID http://orcid.org/0000-0001-5884-6453
QIMR Berghofer Medical Research Institute · AUQueen's University Belfast · GBThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic fibrosis is the central cause of chronic clinical pathology resulting from infection by the blood flukes Schistosoma japonicum or S. mansoni. Much has been elucidated regarding the molecular, cellular and immunological responses that correspond to the formation of the granulomatous response to trapped schistosome eggs. A central feature of this Th2 response is the deposition of collagen around the periphery of the granuloma. To date, traditional histology and transcriptional methods have been used to quantify the deposition of collagen and to monitor the formation of the hepatic granuloma during experimental animal models of schistosomiasis. We have investigated the dynamic nature of granuloma formation through the use of a transgenic mouse model (B6.Collagen 1(A) luciferase mice (B6.Coll 1A-luc

Indexed as

AnimalsCollagenDisease Models, AnimalFemaleHistocytochemistryLiverLiver CirrhosisLuciferasesMaleMiceMice, TransgenicOptical ImagingSchistosoma japonicumSchistosomiasisCollagenLuciferases

Identifiers

PMID30401957
OpenAlexW2890843261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.