Evidence map›Paper›PMID 30401915›Full record

ArticleScientific reports2018

Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice.

Naoyuki Tahara, Hiroko Kawakami, Teng Zhang, David Zarkower, Yasuhiko Kawakami

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  10. Development (Cambridge, England) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Naoyuki TaharaDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.
Hiroko KawakamiDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.
Teng ZhangDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.
David ZarkowerDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.
Yasuhiko KawakamiDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA. kawak005@umn.edu.ORCID http://orcid.org/0000-0002-0043-9705
University of Minnesota · US

Funding

DMRT1 IN MAMMALIAN SEXUAL DEVELOPMENTR01GM059152 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BARDWELL, VIVIAN J, ZARKOWER, DAVID A. · 1999 to 2019
$8.8M
Genetic Regulation of Progenitor Cells in Appendicular Skeletal DevelopmentR01AR064195 · NIAMS · UNIVERSITY OF MINNESOTA · PI KAWAKAMI, YASUHIKO · 2013 to 2022
$3.3M
Stem Cell Biology Training ProgramT32GM113846 · NIGMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2015 to 2019
$712k
NIAMS NIH HHS R01 AR064195NIGMS NIH HHS R01 GM059152NIGMS NIH HHS T32 GM113846
6 · The paper itself

Abstract

Mutations in the SALL4 gene cause human syndromes with defects in multiple organs. Sall4 expression declines rapidly in post-gastrulation mouse embryos, and our understanding of the requirement of Sall4 in animal development is still limited. To assess the contributions of Sall4 expressing cells to developing mouse embryos, we monitored temporal changes of the contribution of Sall4 lineages using a Sall4 GFP-CreER

Indexed as

Adult Germline Stem CellsAnimalsDNA-Binding ProteinsEmbryonic DevelopmentExonsGastrulationGene Expression Regulation, DevelopmentalGene Knock-In TechniquesMaleMiceRNA, MessengerSpermatogoniaSpermatozoaTime FactorsTranscription FactorsDNA-Binding ProteinsRNA, MessengerSall4 protein, mouseTranscription Factors

Identifiers

PMID30401915
PMCPMC6219540
OpenAlexW2899001476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.